Sailaja Pirati
Greater Toronto Area,Canada
Summary
Dynamic Researcher with hands-on experience in in-vitro and in-vivo research,mammalian cell culture, talent for navigating challenges. Brings strong problem-solving skills and proactive approach to new tasks. Known for adaptability, creativity, and results-oriented mindset. Committed to making meaningful contributions and advancing organizational goals.
Overview
13
13
years of professional experience
1
1
Certification
Work History
Lab Manager
McMaster University
02.2024 - Current
- Oversee the collection, entry, verification, management, analysis, and reporting of data
- Use statistical software to analyze data and interpret results
- Design and maintain databases, data collection forms, error checking methods and related programs for efficient collection, analysis, and reporting
- Modify and reconfigure databases to ensure the optimal storage of data and minimize data entry complexities
- Troubleshoot moderately complex computer problems
- Write data management and operations documentation for the project
- Liaise between the project centre and remote project sites and personnel
- Conduct structured project participant interviews
- Ensure that the relevant research methodology is applied and all research material is handled in accordance with established protocols, policies, and procedures
- Develop presentations and present information and training sessions to project personnel and project participants
- Keep project participants informed of project progress through regular reports and newsletters
- Gather and compile information and data required for the preparation of scientific papers, abstracts, and graphs
- Conduct literature searches
- Oversee the extraction and compilation of data required for reports and disseminate data to research groups and collaborating partners
- Implement and maintain the research project budget
- Create financial projections and make adjustments to the research project budget throughout the fiscal year
- Exercise appropriate budget controls, monitor, and reconcile accounts
- Write a variety of letters and memos
- Participate in research project meetings and propose recommendations for procedure modifications and development in the areas of data management, quality control, and assurance
- Write, update, and archive data management and quality assurance conventions
- Respond to inquiries received from project personnel regarding relevant project issues and procedures.
Senior Research Associate
Triumvira Immunologics, Inc.
03.2022 - 12.2023
- Manage mouse colonies, overseeing breeding and genotyping of transgenic animals
- Conduct routine technical procedures in rodents, administering test articles through various routes (intravenous, intramuscular, etc.)
- Monitor animal health, perform anesthesia, and conduct blood sampling
- Demonstrate impeccable tissue culture techniques, including primary cell culture and cell isolation
- Execute euthanasia, tissue collection, and the collection of lymphocytes and splenocytes, along with necropsy procedures
- Coordinate the shipment of samples and their analysis at local laboratories
- Accurately prepare dosing materials, involving calculations and dilutions
- Adhere to study protocols, animal use protocols, and Standard Operating Procedures (SOPs)
- Maintain detailed lab records, whether in paper or electronic formats
- Perform various facility-related procedures, including surgical instrument preparation, record-keeping, inventory maintenance, document review, and database management.
Immunochemistry Quality control Reviewer( support scientific)
Charles River Laboratories
03.2021 - 03.2022
- Manage electronic document life cycle, including creation, revision, archival, retention, and withdrawal/retirement
- Oversee Document Change Control to ensure compliance with regulatory requirements and site practices
- Issue GxP documents (batch records, logbooks, worksheets) for QC, clinical, and commercial manufacturing
- Maintain Procedural Document Binders or electronic equivalents
- Scan and file executed documents physically and electronically, organizing document control file rooms
- Ensure secure and retrievable storage of GMP records, adhering to defined retention periods
- Support periodic document reviews and maintain alignment with the documented quality system and regulatory requirements
- Represent the department in cross-functional project teams
- Provide support during regulatory audits and inspections
- Perform additional assigned duties and responsibilities
- Collaborate with the Scientist to compile and assemble study deliverables in an audit ready state for submission to the Quality Assurance department (QA) and answer QA findings
- Preparing or revision of the study summary (e.g MQS, MVS) when required
- Perform all other related duties assigned.
Toxicology Research
ITR Laboratories Canada Inc.
03.2019 - 03.2021
- Leads and completes scheduled work activities such as preventative maintenance, corrective maintenance, calibrations and troubleshooting
- Administration of substances (IV, gavage, infusion, subcutaneous, IP, inhalation)
- Collection of biological samples (urine, blood, feces) and various parameters (observations, body weight, food consumption, vital signs)
- Assure the wellbeing and welfare of the animals (husbandry)
- Record meticulously study raw data and perform study activities, following the study plan, the established SOPs and the GLP regulation
- Make recommendations for the improvements in the study to the manager
- Review the daily schedule day to day basis.
Doctoral Researcher
JNTU Anantapur
11.2011 - 02.2019
- Set up and conduct biological, microbiological and biochemical tests and laboratory analyses in support of research and quality control in food production, sanitation, pharmaceutical production, biotechnology and other fields
- Applied methods and techniques such as microscopy, histochemistry, chromatography, electrophoresis and spectroscopy
- Performed experimental procedures in agriculture, plant breeding, animal husbandry, biology and biomedical research
- Conducted field research and surveys to collect data and samples of water, soil, and plant and animal populations
- Growing microbe cultures
- Analyse data and prepare reports
- Investigating results for microbiological data
- Using computers and a wide variety of laboratory instruments to carry out experiments
- Ensuring products and processes comply with all relevant SOP's, principles and regulations
- Involved in the production, testing and packing of vials
- Writing up research findings and then producing conclusive reports.
Education
Doctor of Philosophy - PhD - Biotechnology
Jawaharlal Nehru Technological University
Master's degree - Biochemistry
Bangalore University
Bachelor's degree - Microbiology, Biochemistry, Chemistry
Osmania University
Skills
Computer Skills
Laboratory Management
Lab Safety Protocols
Experimental design
Cell Culture
PCR Techniques
Research Planning
Research coordination
Data Management
Certification
- All mouse experiment techniques
- CL2,CL2+
- qPCR
- ELISA
- Tesol
- Discover Your Stress Personality
- How to Use LinkedIn Learning
- Developing Cross-Cultural Intelligence
- Good laboratory practices (GLP)
Publications
- Improved Production of γDecalactone from Castor Oil by UV Mutated Yeast
- Sporidiobolus salmonicolor (MTCC 485)
- Bioactive peptides in waste sheep and goat abbatoir meat products.
- MUTATIONAL STUDIES OF SPORIDIOBOLUS SALMONICOLOR FOR THE PRODUCTION OF γ - DECALACTONE
- PRECLINICAL CHARACTERIZATION AND MODELLING OF ALLOGENEIC Vg9Vd2 TAC T CELLS FOR THE TREATMENT OF SOLID TUMORS
- PRE-CLINICAL CHARACTERIZATION OF ALLOGENEIC Vγ9Vδ2 HER2-TAC T CELLS FOR THE TREATMENT OF HER2-POSITIVE SOLID TUMORS
- 372 TAC-T cells persist and remain functional during and after repeated tumor exposure in vitro and in vivo
- 347 Functional characterization of GUCY2C-TAC T cells for the treatment of colorectal cancer using preclinical models
- 261 Evidence for durable anti-tumor responses by TAC-T cells in preclinical models of solid tumors
- Bioactive peptides in waste sheep and goat abbatoir meat products.
Languages
English
Full Professional
Telugu
Native or Bilingual
Hindi
Full Professional
Timeline
Lab Manager
McMaster University
02.2024 - Current
Senior Research Associate
Triumvira Immunologics, Inc.
03.2022 - 12.2023
Immunochemistry Quality control Reviewer( support scientific)
Charles River Laboratories
03.2021 - 03.2022
Toxicology Research
ITR Laboratories Canada Inc.
03.2019 - 03.2021
Doctoral Researcher
JNTU Anantapur
11.2011 - 02.2019
Doctor of Philosophy - PhD - Biotechnology
Jawaharlal Nehru Technological University
Master's degree - Biochemistry
Bangalore University
Bachelor's degree - Microbiology, Biochemistry, Chemistry
Osmania University
Similar Profiles
Yassine BenkandilYassine Benkandil
Graduate Researcher at McMaster UniversityGraduate Researcher at McMaster University
Antonia PereraAntonia Perera
Exam Invigilator (Part Time) at McMaster UniversityExam Invigilator (Part Time) at McMaster University
Kera JonesKera Jones
Medical Secretary II- Patient Services at McMaster UniversityMedical Secretary II- Patient Services at McMaster University
Kyla SantosKyla Santos
Biology Laboratory at McMaster UniversityBiology Laboratory at McMaster University
Zacharie AsselinZacharie Asselin
Founder - Regional Sales Director at Swipe FinancialFounder - Regional Sales Director at Swipe Financial