Saeed Khalili

A tenacious and passionate Stem Cell biologist. Highly-qualified Scientist, Research & Laboratory Manager with top-notch leadership, planning and problem-solving abilities. Open and clear communicator with disciplined and thorough approach.

• Complete paperless policy in the laboratory and barcoding system for reagents inventory.
• Achieved and collaborated in funding applications that have received over 600K CAD from the federal, provincial governments and biotech/pharma.
• Research was published (first author) in Stem Cell Res journal2018.
• Influenced & consulted the strategic partnerships between the laboratory and industry,plus, other academic partners, including Center for Commercialization of Regenerative Medicine (CCRM) and biotech/pharma Endogena Therapeutics Inc.
• Developed and established a cell and stem cell therapy for Type I Diabetes and Xerostomia (dry mouth).
• Supervised team of 5 staff members and 4 students.

• 2006-present International Society for Stem Cell Research (ISSCR). Scientific research review in the journal of Stem Cell Research
• 2010-present Canadian Stem Cell Network Holding workshop

• S. Khalili et al., (2016). Continuous blocking of the differentiation of retinal progenitors derived from retinal stem cells into non-cone fates permits the isolation of large cone photoreceptor specific retinal progenitor clones. Till & Mcculloch (TMM), Whistler, BC, Canada
• S. Khalili et al., (2015). Differentiation of adult retinal stem cells into cone photoreceptor-specific progenitors. International Society for Stem Cell Research (ISSCR), Stockholm, Sweden
• S. Khalili et al., (2014). Differentiation of adult retinal stem cells into rod photoreceptor. International Society for Stem Cell Research (ISSCR), Vancouver, Canada
• S. Khalili et al., (2011). Mesenchymal precursor cells restore salivary gland function in Non-Obese Diabetic mice with Sjogren’s syndrome. International Society for Stem Cell Research (ISSCR), Toronto, Canada
• S. Khalili et al., (2008). Splenocytes restore salivary gland function in mice with Sjogren’s Syndrome. International Association for Dental Research (IADR), Toronto, Canada

• 2019-01-01, present, Research and Laboratory Manager, Department of Medicine, University of Toronto, Toronto, ON, Initiated and collaborated in multiple successful grant applications., Nex Generation Sequencing (including spatial transcriptome) design and data analysis (using, R and Python)., Completed paperless policy in the laboratory, Train, teach, and supervise laboratory staff and graduate students including medical residents., Liaise between the laboratory and private sector for strategic partnership and collaboration., Involve in clinical trial including design, data collection, and analysis across multiple Canadian sites., Oversee day-to-day operation, monitor research progress, and manage budget., Inspect the workplaces and laboratories as a member of Joint Health & Safety Committees.
• 2016-01-01, 2016-01-01, Research Associate, Department of Molecular Genetics, University of Toronto, Toronto, ON, Supported funding applications that have received over 600K in funding, federal, provincial and biotech/pharma partner to support our stem cell research projects (CIHR, Fighting For Blindness; FFB, Ontario Institute For Regenerative Medicine; OIRM, and Medicine by Design; MbD)., Supported the strategic partnerships between the lab and industry, plus other academic partners, including Center for Commercialization of Regenerative Medicine (CCRM) and biotech/pharma Endogena Therapeutics Inc (2016-2019)., Unique Scientific Achievement: establishment of producible conephotoreceptor differentiation(from 0.5% togreater than60% purity). Work was published in Stem Cell Res journal2018.
• 2012-01-01, 2016-01-01, Postdoctoral Fellow, Department of Molecular Genetics, University of Toronto, Toronto, ON, Involved in the pre- clinical experimental strategy, design, and implementation of the drug discovery program in an industry-academic partnership with Swiss biopharmaceutical startup Endogena Therapeutics., Assisted with supervision of personnel: rotation, graduate, and undergraduate students., Performed bench works including in-vivo and in-vitro experiments (transplantation).
• 2007-01-01, 2012-01-01, Doctoral Graduate Student, McGill University, Montreal, QC, Developed a cell and stem cell therapy for Xerostomia (dry mouth) in a mouse model using stem/progenitor transplantation systemically and locally., Established a strategy to eliminate autoreactive T-cell while regenerating the salivary and pancreas glands in Sjogren’s syndrome and Type 1 Diabetes (T1D) animal model., Supervised undergraduate, medical, and dental students summer research training., Contributed to 10 research articles including three first author papers and received six awards/scholarships to support my research.

• 2013-01-01, Postdoctoral Fellowship, Foundation Fighting Blindness Canada (FFB) postdoctoral award.
• 2012-01-01, Prestigious CIHR Postdoctoral Fellowship, The Canadian Institutes of Health Research (CIHR) Biotherapeutic postdoctoral fellowship
• 2012-01-01, McGill Graduate Award, McGill University Faculty of Dentistry Studentship
• 2011-01-01, Dr. Lyon Bercovitch Memorial Award, La Fondation de l’Ordre des dentistes du Québec (FODQ) Doctoral award McGill University PhD award
• 2011-01-01, RSBO studentship award, Le Réseau de recherche en santé buccodentaire et osseuse Quebec Student Scholarship
• 2010-01-01, Principal’s Graduate Fellowship, McGill University Graduate Award
• 2009-01-01, The Excellent Recruitment Student Fellowship, McGill University Graduate Studies Award
• 2009-01-01, First rank university entrance exam nationwide, National Medical University Entrance award (nationwide)

• S. Naderi-Azad, D. Croitoru, S. Khalili, L. Eder, V. Piguet, J Invest Dermatol. 67-473.e1 (2021).
• B. G. Ballios, S. Khalili, M. S. Shoichet, D. van der Kooy, Adv Exp Med Biol. 551–555 (2019).
• S. Khalili et al., Stem Cell Res. 33, 215–227 (2018).
• G. A. Elghanam, Y. Liu, S. Khalili, D. Fang, S. D. Tran, Methods Mol Biol. 1553, (2017).
• S. Khalili et al., Cytotherapy. 16, 412–423 (2014).
• S. D. Tran, S. Khalili et al., PLoS One. 8, e61632 (2013).
• F. Tamimi, S. Khalili et al., Eur Cell Mater. 25, 22–36 (2013).
• R. Khosravi, S. Khalili et al., Mediators Inflamm. 2013, 728987 (2013).
• S. Khalili et al., PLoS One. 7, e38615 (2012).
• Y. Sumita, S. Khalili et al., Int J Biochem Cell Biol. 43, 80–87 (2011).
• Y. Kuriki, S. Khalili et al., J Vis Exp, 3074 (2011).
• S. D. Tran, Y. Sumita, S. Khalili, Int J Biochem Cell Biol. 43, 5–9 (2011).
• S. Khalili et al., Int J Biochem Cell Biol. 42, 1893–1899 (2010).
• S. D. Tran, S. Khalili et al., Ann Rheum Dis. 66, 812–814 (2007).

• 2023 Big Data Management Systems and Tools
• 2022 Statistic for Data Science
• 2022 Project Implementation & Control
• 2021 Leading Projects in Organizations
• 2021 Foundation of Project Management
• 2021 Data Science with Python & R
• 2020 Good Manufacturing Practice and Good Laboratory Practice

• Project Management (PMP)
• Data Science
• GMPs/GLPs