Ana Luiza Abdalla dos Santos
Ph.D. Candidate
Montreal,QC
Summary
Expertise in infectious disease and immunobiology for + 7 years. Established several collaborations resulting in 3 journal articles, 2 published and one under review, as co-author and 2 first author in preparation. Involved with biomedical research for +7 years, in multiple laboratories, and different topics (e.g., Tuberculosis, Chagas’ disease, and HIV), leading, planning, and executing all stages of the project. Effective communication skills as a result of oral and poster presentations in scientific conferences, weekly lab meetings. Technical skills: Primary cell culture, Spectral Flow Cytometry, Immunofluorescence
Overview
9
9
years of professional experience
10
10
years of post-secondary education
Work History
Immuno-virology Researcher
McGill University/ Lady Davis Institute- Jewish General Hospital
1 2020 - Current
- Managing and executing project designed to understand the impact of autophagy in HIV latency through screening FDA-approved drugs, aiming to repurpose it towards a functional HIV cure, resulting in journal article to be submitted and a thesis
- Collaborating in a multi-team research projects aiming to elucidate the mechanism of HIV egress from infected cells and in the role of host proteins during HIV replication, which resulted in two papers, one published and the other currently under review
- Executed projects in an international collaboration with a research group in Chile aiming to elucidate the impact of host protein in HIV-1 protein expression, leading to the publication in a peer-reviewed journal
- established the differentiation of primary CD4+ T cells in central memory to study HIV-1 latency in a dual reporter viral system
- Optimized the use of Spectral Flow cytometry to evaluate isolated lysosomes from HIV infected macrophages
- Wrote a review article about HIV latency published in the Journal Viruses.
Immunology Researcher
Universidade Federal de Santa Catarina
08.2017 - 08.2019
- Led a side of a project with the aim of elucidating the role of Rv1419 gene from Mycobacterium tuberculosis during infection in macrophages
- Collaborated, additionally, with different arms of this project
- Executed experiments in mice, requiring ability to isolate bone marrow and differentiate it in macrophages in cell culture conditions
- Presentation of projects and results in weekly lab meetings and annual Graduate Research Day
- Taught Pharmacology for one semester in an undergraduate course.
Immunology Researcher
Universidade Federal do Triângulo Mineiro
09.2015 - 06.2017
- Worked on a project that aimed in elucidating the immunopathology of Chagas’ Disease during the clinical presentation of megacolon in mice, and further megaesophagus in humans
- Collaborated in a project aiming to understand the immunopathology of Eczema, and the immunomodulatory effects of the treatments
- Executed the experiments, which involved blood collection, PBMC isolation and further Flow cytometry.
Education
Ph.D. Microbiology And Immunology - HIV Latency
McGill University
Montreal, QC 01.2021 - 01.2025
M.Sc. Pharmacology - Innate Immunity And Tuberculosis
Universidade Federal De Santa Catarina
Brazil 08.2017 - 08.2019
B.Sc. Biomedical Science - Chagas' Disease And Immune Response
Universidade Federal Do Triangulo Mineiro
Brazil 08.2013 - 08.2017
Skills
Project management
Written Communication
Oral Communication
FlowJo
Prism GraphPad
Imaris
Adobe Illustrator
Microsoft Office
Pronouns
She/her
Languages
English
Full Professional
French
Limited Working
Spanish
Limited Working
Portuguese
Native or Bilingual
Additional Information
Publications:
1- Viruses 2024, 16, 229; https://doi.org/10.3390/v16020229
2- Nucleic Acids Research 2024, 52, 2625-2644; https://doi.org/10.1093/nar/gkad1221
3- iScience, 2024. Accepted for publication. An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity
Timeline
Ph.D. Microbiology And Immunology - HIV Latency
McGill University
01.2021 - 01.2025
M.Sc. Pharmacology - Innate Immunity And Tuberculosis
Universidade Federal De Santa Catarina
08.2017 - 08.2019
Immunology Researcher
Universidade Federal de Santa Catarina
08.2017 - 08.2019
Immunology Researcher
Universidade Federal do Triângulo Mineiro
09.2015 - 06.2017
B.Sc. Biomedical Science - Chagas' Disease And Immune Response
Universidade Federal Do Triangulo Mineiro
08.2013 - 08.2017
Immuno-virology Researcher
McGill University/ Lady Davis Institute- Jewish General Hospital
1 2020 - Current
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