Overview
Work History
Education
Skills
Timeline
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ZHILIN XU

Toronto,Canada

Overview

6
6
years of professional experience

Work History

Machine Learning Software Engineer

OTA Technologies Inc.
05.2022 - Current
  • Built an AI agent that controls mouse and keyboard to help students auto apply jobs using python and pyautogui that improves efficency by 68%
  • Built a synthetic dataset generation pipeline that is used to finetune language models with over 325k entries
  • Fine tuned a large language model mistral-7b model on private dataset
  • Built a local knowledge base using langchain open source vector embedding and faiss database

Bioinformatics Intern

Roche Canada
01.2022 - 04.2022
  • Developed a dashboard through data modification, R programming, and R Shiny development to address concerns associated with the primary analysis of Phase III trials' clinical patient and biomarker data.
  • Delivered visualized output to resolve analytic challenges for clinical scientist.
  • Contributed to the enhancement of data analysis pipelines and workflows for analyzing single cell sequencing results using Seurat package.

Research Assistant

Advanced Molecular Diagnostics Laboratory, Mont Sinai Hospital
06.2021 - 01.2022
  • Developed a systematic reporting pipeline to quantitatively analyze variants sourcing from more than 1500 COVID-19 positive patient genomes.
  • Performed data filtration and variant analysis according to ACMG guidelines and internal standards.
  • Provide bioinformatics support using PLINK and command line for association studies between suspicious variants and COVID-19 phenotypes, severity, and serology data.
  • Reported clinically significant pathogenic variants to patients for genetic counseling and made the database available for further research usage.

RESEARCH INTERN

Apexigen Co.
07.2019 - 08.2019
  • Supported the development of a novel anti-cancer drug in phase 2 clinical trial by performing ELISA-based biomarker validation and research data compilation.
  • Contributed to the translational team's efforts in advancing to Phase 3 applications.

RESEARCH INTERN

The Lu's Lab, Pathology Dept., Standford Medicine
06.2018 - 08.2018
  • Conducted wet-lab-based research on Drosophila models to address the role of amyloid precursor protein in Alzheimer's disease.
  • Performed microdissection, immunohistochemistry staining, confocal microscopy screening, western blotting, and other wet-lab procedures to obtain high-quality data.
  • Findings contributed to subsequent research projects in the lab.

Education

M.H.Sc - Medical Genomics

University of Toronto - St.George
Toronto, ON
04.2022

B.S - Immunology & Physiology

University of Toronto - St. George
Toronto, ON
06.2020

Skills

  • Proficiency in R & Command Line
  • scRNA-seq Result Analysis
  • Python Programming
  • GWAS performance using PLINK
  • Metagenomics Analysis
  • Data curation & visualization
  • Machine Learning
  • Statistical analysis techniques
  • Teamwork and Collaboration
  • Problem-solving aptitude

Timeline

Machine Learning Software Engineer

OTA Technologies Inc.
05.2022 - Current

Bioinformatics Intern

Roche Canada
01.2022 - 04.2022

Research Assistant

Advanced Molecular Diagnostics Laboratory, Mont Sinai Hospital
06.2021 - 01.2022

RESEARCH INTERN

Apexigen Co.
07.2019 - 08.2019

RESEARCH INTERN

The Lu's Lab, Pathology Dept., Standford Medicine
06.2018 - 08.2018

M.H.Sc - Medical Genomics

University of Toronto - St.George

B.S - Immunology & Physiology

University of Toronto - St. George

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