Summary
Overview
Work History
Education
Skills
Conference Presentations
Equipment Proficiency
Awards
Publications
Conference Publications
Academic Training
Languages
Certification
Affiliations
References
Timeline
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Willem Rijnbout St James

Willem Rijnbout St James

Montreal,Canada

Summary

Community-oriented graduate researcher with expertise in communication, experimental design/execution, and data analysis. Proven ability to present complex findings clearly and contribute positively as a team player. Expertise in both in vivo and in vitro preclinical models, emphasizing statistical analysis and data interpretation. Aims to leverage strong analytical skills, collaborative spirit, and interpersonal abilities to drive impactful research outcomes.

Overview

7
7
years of professional experience
1
1
Certification

Work History

Graduate Researcher

Meakins-Christie Laboratories
07.2022 - Current
  • Designed and executed pre-clinical in vivo and in vitro experiments to investigate the intersection between the aryl hydrocarbon receptor and molecular signaling pathways implicated in idiopathic pulmonary fibrosis.
  • Presented research findings at various global conferences.
  • Directed and advised a senior undergraduate student throughout a year-long, lab-based honors project.
  • Prepared new research proposals and applied for grants.
  • Analyzed data using statistical methods and software packages such as SAS, SPSS, and R.

Laboratory Intern

Maine Medical Center Research Institute
08.2021 - 03.2022
  • Conducted research on Collagen Triple Helix Repeat Containing 1 (CTHRC1).
  • Engineered stable CHO cell lines using various CTHRC1 constructs.
  • Analyzed differential expression patterns of CTHRC1 across multiple tissues in response to particular environmental stress exposures.

Student Researcher

University of New England
01.2020 - 01.2022
  • Research overseen by Dr. Silvia E. Smith focused on vascular remodeling due to chronic inflammation.
  • Performed in-silico pathway analysis to elucidate intersections between CTHRC1, NFKb, TGF-b, and SMAD using Ingenuity Pathway Analysis.
  • Collaborated with Dr. Smith and academic institutions to conduct research on serum CTHRC1 expression in interstitial lung disease cohorts.
  • Characterized involvement of CTHRC1 in ILD pathogenesis using initial in-silico methods.

Route Setter and Climbing Coach

OffSite Climbing
Montreal, QC
01.2025 - Current
  • Oversee the development of commercial-grade boulders during open-invitation setting events.
  • Facilitate community-focused onBOARD initiative, engaging 10-12 participants per session. Designed and implemented a curriculum to pinpoint improvements in movement, techniques, and tactics.

Route Setter

Allez Up Climbing Center
Montreal
04.2023 - 11.2024
  • Collaborated with experienced route setters at Allez Up's three locations.
  • Designed boulder problems prioritizing accessibility, enjoyment, and challenge.
  • Set for various competitions, including Mile-End Send and Jackalope.

Climbing Coach

Self Employed
08.2020 - 01.2023
  • Executed climbing training programs for adults.
  • Promoted services via digital platforms, printed materials, and interpersonal communication.
  • Developed comprehensive plans for both wall and off-wall movements through supplementary training.
  • Incorporated approaches inspired by the works of thought leaders including Tyler Nelson, Neil Gresham, and others.

Assistant Climbing Coach

Salt Pump Climbing Co.
01.2020 - 06.2020
  • Received training in coaching principles under head coach.
  • Guided youth climbers (ages 10-16) through strength, endurance, power endurance, and mock competition phases.
  • Helped young athletes view failure as a growth opportunity.

Nursing Assistant

Clinique Assalam
Tangier, Morocco
08.2018 - 12.2018
  • Assisted nurses by transporting, cleaning, and feeding patients on the medical-surgical floor.
  • Ensured continuous availability of necessary supplies by frequently restocking gloves, sanitation products, and linens.
  • Gained insight into healthcare disparities that effect resource allocation in countries like Morocco.

Orientation Leader

University of New England
06.2018 - 08.2018
  • Coordinated and guided pre-orientation programs to ensure a positive introduction to campus life.
  • Promoted interaction through organized icebreaker games for students.
  • Fostered an open environment for students to discuss their concerns and excitement about beginning undergraduate studies.

Education

Master of Science - Pathology

McGill University
Montreal, Quebec, Canada
03.2025

Bachelor of Science - Medical Biology

University of New England
Biddeford, Maine, USA
01.2021

Skills

  • Project management
  • Public Speaking
  • Effective communication
  • Technical writing
  • Experimental Design
  • Mammalian Cell Culture
  • Pre-clinical mouse models of disease
  • Western Blot
  • Genotyping
  • ELISA
  • qPCR
  • CRISPR-Cas9 Technology
  • Mass-spectrometric proteomic data analysis
  • Experienced in Brightfield Microscopy Techniques
  • siRNA Gene Knockdown
  • Experience with MTT and LDH Assays
  • Histology
  • Data Statistical Analysis
  • Statistical Data Interpretation
  • Proficient Coding in R/Python
  • Expertise in Scireq FlexiVent
  • Expertise in Confocal Laser Scanning Microscopy

Conference Presentations

  • 2025, Defining the Aryl Hydrocarbon Receptor as a Driver of Pulmonary Fibrosis, Poster presented at the Rare Disease Research Day (RareDIG) at the Montreal Neurological Institute.
  • 2024, The Aryl Hydrocarbon Receptor: Implications in Pulmonary Fibrosis., Poster presented at Meakins Christie Laboratories Respiratory Research Day.
  • 2023, The Aryl Hydrocarbon Receptor: New Implications in Fibrosis., Poster presented at 50th Anniversary Research Conference of the Meakins Christie Laboratories.
  • 2022, Plasma Levels of Collagen Triple Helix Repeat Containing 1 (CTHRC1) as a Potential Biomarker in Interstitial Lung Disease., Abstract accepted to ICBCM 2022: International Conference on Biomarkers and Clinical Medicine.
  • 2021, Plasma Levels of Collagen Triple Helix Repeat Containing 1 (CTHRC1) in an Interstitial Lung Disease Cohort., Poster presented at the 2021 College of Arts and Sciences Spring Research Symposium, University of New England, Biddeford, ME.
  • 2020, CTHRC1 regulation of NFkB pathway in vascular remodeling resulting from chronic age-related inflammation., Poster presented at the 2020 College of Arts and Sciences Fall Research Symposium, University of New England, Biddeford, ME.

Equipment Proficiency

  • Scireq FlexiVent (Murine Pulmonary Function Analysis)
  • Zeiss Confocal Laser Scanning Microscope 780/800
  • BioRad ChemiDoc Chemiluminescence Imaging System

Awards

  • 01/01/23, Meakins-Christie Laboratories 2023 Collaborative Research Award, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
  • 01/01/22, Best in Medicine and Health Science at the International Conference on Biomarkers and Clinical Medicine., "Plasma Levels of Collagen Triple Helix Repeat Containing 1 (CTHRC1) as a Potential Biomarker in Interstitial Lung Disease"
  • 01/01/22, Summa Cum Laude (High Honours), University of New England, Biddeford, Maine, USA
  • 01/01/22, Dean's Honors list, University of New England, Biddeford, Maine, USA, 2018 - 2022

Publications

01/01/23, Alluli, A., Rijnbout St James, W., Eidelman, D. H., Baglole, C. J., Dynamic relationship between the aryl hydrocarbon receptor and long noncoding RNA balances cellular and toxicological responses., Biochemical pharmacology, 216, 115745, https://doi.org/10.1016/j.bcp.2023.115745

Conference Publications

  • 01/01/25, W. Rijnbout St James, E. Wilson, E. Marcotte, J. Ding, P. Nair, D. H. Eidelman, C. Baglole, Defining the Aryl Hydrocarbon Receptor as a Driver of Pulmonary Fibrosis., American Thoracic Society. Cellular/Molecular Investigation /Respiratory Cell and Molecular Biology (RCMB) Group.
  • 01/01/22, Rijnbout-St.James Willem, Lindner Volkhard, Scholand Mary Beth, Ashton M. Tillett, DiGennaro Michael Jude, Smith Silvia Enrica, Plasma Levels of Collagen Triple Helix Repeat Containing 1 (CTHRC1) as a Potential Biomarker in Interstitial Lung Disease., World Academy of Science, Engineering and Technology. International Journal of Biomedical and Biological Engineering., 16, 03, 2022

Academic Training

  • Masters of Science (M.Sc.), Pathology, McGill University, 09/01/22, Present, Montreal, Quebec, Canada
  • Bachelor of Science (B.Sc.), Medical Biology, University of New England, 09/01/17, 05/01/21, Biddeford, Maine, USA

Languages

English
Native/ Bilingual
French
Limited

Certification

  • ICH Guidance E6(R2) GCP (International Council for Harmonisation-Good Clinical Practice) - CANTRAIN | Clinical Trials Training Programs (Credential ID 1672 SA.L2.C1.EN.V1)

Affiliations

  • Avid rock climber and home cook

References

References available upon request.

Timeline

Route Setter and Climbing Coach

OffSite Climbing
01.2025 - Current

Route Setter

Allez Up Climbing Center
04.2023 - 11.2024

Graduate Researcher

Meakins-Christie Laboratories
07.2022 - Current

Laboratory Intern

Maine Medical Center Research Institute
08.2021 - 03.2022

Climbing Coach

Self Employed
08.2020 - 01.2023

Student Researcher

University of New England
01.2020 - 01.2022

Assistant Climbing Coach

Salt Pump Climbing Co.
01.2020 - 06.2020

Nursing Assistant

Clinique Assalam
08.2018 - 12.2018

Orientation Leader

University of New England
06.2018 - 08.2018

Master of Science - Pathology

McGill University

Bachelor of Science - Medical Biology

University of New England
Willem Rijnbout St James