Stacey Barnes

Clinical-stage cell therapy biotechnology company advancing toward commercial readiness.

Commercial Strategy & Business Transformation

• Developed the enterprise technology strategy supporting Kyverna's transition from clinical-stage biotechnology company to commercial readiness.
• Partnered with Executive Leadership to align technology investments with manufacturing, regulatory, quality, commercial, and corporate priorities.
• Created multi-year technology roadmaps balancing rapid organizational growth with disciplined investment and regulatory compliance.
• Served as strategic advisor on technology decisions supporting commercialization, operational scalability, and enterprise risk management.

Digital Strategy & Enterprise Architecture

• Developed the Kyverse enterprise digital strategy establishing a scalable architecture supporting future commercial operations.
• Designed enterprise integration strategy connecting ERP, CRM, Manufacturing, Quality, Clinical, Regulatory, and Commercial platforms.
• Championed composable architecture and low-code solutions that improved business agility while reducing software costs.
• Established enterprise governance for technology investments, portfolio prioritization, and executive decision making.

Commercial Readiness

• Led technology strategy supporting Commercial, Manufacturing, Supply Chain, Regulatory Affairs, Finance, and Quality organizations.
• Directed evaluation and implementation planning for commercial technology platforms supporting patient enrollment, reimbursement, scheduling, manufacturing, fulfillment, and customer engagement.
• Partnered with Commercial leadership to develop an integrated digital ecosystem supporting future launch operations.
• Balanced implementation timelines with BLA milestones, organizational readiness, and long-term scalability.

Regulatory, Quality & Compliance

• Directed technology initiatives supporting FDA inspection readiness and Biologics License Application (BLA) activities.
• Oversaw governance of GxP systems supporting Quality, Manufacturing, Technical Operations, and Regulatory Affairs.
• Led cybersecurity strategy, SOX IT General Controls, IT compliance, and enterprise technology risk management.
• Partnered closely with Quality and Regulatory organizations to ensure technology enabled inspection readiness and commercialization objectives.

Leadership

• Built and led Infrastructure, Cybersecurity, Enterprise Applications, Data, Compliance, and PMO organizations.
• Managed multimillion-dollar technology budgets and strategic vendor relationships.
• Established governance processes improving executive visibility into technology investments, project execution, and business outcomes.
• Fostered a collaborative technology organization focused on business partnership, operational excellence, and innovation.

• Built the company's first enterprise IT organization supporting rapid organizational growth.
• Developed enterprise technology strategy aligned with manufacturing, research, and corporate objectives.
• Successfully implemented validated GxP platforms including Sage X3 ERP, TrackWise Digital (QMS, DMS, TMS), and Nuvolo CMMS.
• Established IT governance, cybersecurity, infrastructure, and managed services supporting a rapidly growing workforce.
• Partnered across Operations, Manufacturing, Quality, Finance, and Research to build scalable technology capabilities.

Progressively promoted through executive leadership positions overseeing enterprise applications, infrastructure, cybersecurity, PMO, and global IT operations supporting more than 1,800 employees worldwide.

Selected accomplishments:

• Directed a $17 million enterprise transformation modernizing core business systems across Finance, Supply Chain, HR, Sales, and Manufacturing.
• Implemented Oracle ERP, Oracle HCM, Oracle CPQ, Oracle EPBCS, Oracle GTM, and enterprise integrations.
• Reduced annual IT operating expenses by $3.2 million through strategic portfolio optimization.
• Presented enterprise technology strategy and investment roadmaps to Executive Leadership and Board of Directors.
• Built enterprise security strategy and governance supporting global operations.
• Established IT policies and procedures resulting in 100% successful SOX audits with no material weaknesses or deficiencies.

• Sephora — eCommerce Project Manager
• Terrace Consulting — Product Group Manager
• The Doctors Company — Manager, Business Systems Analysis
• Terrace Consulting — Consulting Manager
• Pacific Gas & Electric — Analyst Programmer