Shehreen Khan

Motivated student currently finishing a BSc in Biochemistry and looking for MSc research opportunities. Previous background in investigating molecular protein-protein interactions via wet-lab and in silico methods. Resourceful and adaptable individual with extensive experience developing and conducting experiments to document results for studies. Comfortable handling complex issues, meeting strict deadlines and adjusting to rapidly changing conditions. Organized and dependable candidate successful at managing multiple priorities with a positive attitude. Willingness to take on added responsibilities to meet team goals.

• Investigated binding interactions between C1B receptors and CRIP1a protein to optimize neurotransmitter release between axons.
• Transformed competent cells to express protein and used fluorescence analysis to visualize binding between WT and mutant strains.
• Mutant strains had single or double AA mutations to disrupt pi-pi bonds within the active site to see the overall effect on active site hydrogen-bond network stabilization.
• Used MD simulations to visualize binding between proteins and examine binding sites/affinities.