Sharmin Begum

• Hardworking and highly motivated researcher with a robust background in immunology,molecular biology, microbiology, biochemistry and virology.
• Expert in host-pathogen interaction and viral pathogenesis.
• Leveraging skills in molecular biology techniques, cell culture, Immunofluorescence and immune profiling.
• Self-developed and reliable team member, and capable of working in a highly paced research environment and meeting deadlines.
• Skilled in both technical methodologies and collaborative project management.

Canadian

• Basic and advanced laboratory training for undergrads and master's students.
• Assisted master's students in designing experiments for their thesis.

• Richard and Edith Strauss Postdoctoral Fellowship in Medicine 2023, McGill University.
• CAHR Academic Scholarship 2023.
• IRCM Postdoctoral fellowships for 2021 and 2022.
• HPI NSERC CREATE studentship scholarship for 2016 and 2017.
• Histochemical Society trainee travel award, Experimental Biology meeting (2016).
• Intersociety Council for Pathology Information (ICPI) Travel Award, Experimental Biology meeting (2015).
• Recruitment Award, University of Calgary (2013).
• Dean’s Award for academic excellence, Faculty of Biological Sciences, University of Dhaka (2011).

1. *Tiwari S, *Begum S, Moreau F, Gorman H and Chadee K (2021) Autophagy is required during high MUC2 mucin biosynthesis in colonic goblet cells to contend metabolic stress. Am J Physiol Gastrointest. Liver Physiol. Impact Factor (IF): 4.87 (* Denotes equal contribution).

2. Begum S, Moreau F, Dufour A, and Chadee K (2021) Entamoeba histolytica exploits the autophagy pathway in macrophages to trigger inflammation in disease pathogenesis. Mucosal Immunology. IF: 9.0

3. Begum S, Gorman H, Chadha A, and Chadee K (2021) Entamoeba histolytica. Trends Parasitol. IF: 10.5

4. Begum S, Gorman H, Chadha A, and Chadee K (2020) Role of inflammasomes in innate host defense against Entamoeba histolytica. J Leukoc Biol. IF: 6.0

5. Begum S, Moreau F, Leon Coria A, and Chadee K (2019) Entamoeba histolytica stimulates the alarmin molecule HMGB1 from macrophages to amplify innate host defenses. Mucosal Immunology. IF: 9.0

6. St-Pierre J, Moreau F, Cornick S, Quach J, Begum S, et al. (2017) The macrophage cytoskeleton acts as a contact sensor upon interaction with E. histolytica to triggerIL-1β secretion. PLOS Pathogens. IF: 6.7

7.  Liu J, Gratz J, Amour C, Nshama R, Walongo T, Maro A, Mduma E, Platts-Mills J, Boisen N, Nataro J, Haverstick DM, Kabir F, Lertsethtakarn P, Silapong S, Jeamwattanalert P, Bodhidatta L, Mason C, Begum S, et al. (2016) Optimization of Quantitative PCR Methods for Enteropathogen Detection. PLoS One. IF: 3.7

8. Taniuchi M, Platts-Mills JA, Begum S, et al. (2016) Impact of enterovirus and other enteric pathogens on oral polio and rotavirus vaccine performance in Bangladeshi infants. Vaccine. IF: 4.9

9. Gilchrist CA, Petri SE, Schneider BN, Reichman DJ, Jiang N, Begum S, et al. (2015) Role of the Gut Microbiota of Children in Diarrhea Due to the Protozoan Parasite E. histolytica. J Infect Dis. IF: 6.4

10. Begum S, Quach J, and Chadee K (2015) Immune Evasion Mechanisms of Entamoeba histolytica: Progression to Disease. Front Microbiol. IF: 6.0

11. Liu J, Lurain K, Sobuz SU, Begum S, et al. (2015) Molecular genotyping and quantitation assay for rotavirus surveillance. J Virol Methods. IF: 2.6

12. Taniuchi M, Begum S, et al. (2015) Kinetics of poliovirus shedding following oral vaccinationas measured by quantitative reverse transcription-PCR versus culture. J Clin Microbiol. IF: 5.9

13. Liu J, Kabir F, Manneh J, Lertsethtakarn P, Begum S, et al. (2014) Development and assessment of molecular diagnostic tests for 15 enteropathogens causing childhood diarrhea: a multicentre study. The Lancet Infectious Diseases. IF: 56.3

14. Platts-Mills JA, Liu J, Gratz J, Mduma E, Amour C, Swai N, Taniuchi M, Begum S, et al. (2014) Detection of Campylobacter in stool and determination of significance by culture, enzyme immunoassay, and PCR in developing countries. J Clin Microbiol. IF: 5.9

15. Taniuchi M, Sobuz SU, Begum S, et al. (2013) Etiology of diarrhea in Bangladeshi infants in the first year of life analyzed using molecular methods. J Infect Dis. IF: 6.4

• IRCM Scientific Forum, 2022, Quebec, Canada. (Flash Talk)
• Canadian Association for HIV Research 2023, Quebec City, Quebec, Canada. (Oral)
• CanCURE Annual Meeting, 2022, Montreal, Quebec, Canada. (Flash Talk)
• IRCM Scientific Forum, 2022, Orford, Quebec, Canada. (Poster)
• Canadian Association for HIV Research 2022. (Poster)
• Experimental Biology 2017, Chicago, USA. (Oral and Poster)
• AMOEBAC 2016, New Delhi, India. (Oral)
• Experimental Biology 2016, San Diego, USA. (Oral)
• XVII International seminar on Amediasis 2016, Campeche, Mexico. (Oral)
• Experimental Biology 2015 Boston, MA, USA. (Oral)
• Canadian Digestive DiseasesWeek (CDDW) 2015, Calgary, Canada. (Oral and Poster)
• Banff Inflammation Workshop (BIW) 2015, Calgary, Canada. (Poster)

1. Kris Chadee, PhD

Microbiology, Immunology, and Infectious Diseases 

University of Calgary

Phone: +1 403-210-3975

Email: kchadee@ucalgary.ca

2. Eric A. Cohen, PhD (Director of the Human Retrovirology unit, IRCM)

Microbiology, Infectiology, and Immunology 

University of Montreal

Phone: +1 514-987-5804

Email: eric.cohen@ircm.qc.ca