Shakila Sultana

Good track record of academic and research excellence with great communication skill. Health Sciences research graduate investigating cell death mechanisms underlying nuclear lamina pathology in neurons. Highly motivated and result-driven person with focus on continuous learning, growth, and accountability. More than 3 years of experience in teaching, research, and supervising undergrad students with leadership aptitude.

Biological Technician (Tech-3), University of Manitoba, 02/01/23, 01/31/24 (end of term and now in maternity leave)

• HSGSA Poster Award and Manitoba Medical College Foundation - Graduate Student Travel Awards at 2023 Manitoba Student Health Research Forum - MSHRF
• Emergent Biosolutions CHRIM Trainee Development award (Fall 2022 and Winter 2023)
• Research Completion Scholarship (Winter 2022)
• Faculty of Graduate Studies Travel Award (06/01/22)
• UMGSA Conference Grant (08/01/22)
• University of Manitoba Graduate Fellowship (2020-21)
• Research Manitoba and University of Manitoba Rady Faculty of Health Sciences (RHFS) entrance scholarship 2020
• International Graduate Student Entrance Scholarship (2020)

• Module I: Advanced Bioinformatics & Module III: NGS (Methylseq), Arraygen, 05/01/23.
• Graduate Professional Development for trainees, CHRIM, Spring 2022.
• Graduate Teaching Program (GTP, Level 1) University of Manitoba.
• Hands on animal training and Certification (Rats and mice including general handling, injections, and surgery), University of Manitoba, 2019.
• Hands on training on computational biology in infectious diseases, Summer School 2017, Quoy Nohn, Vietnam on Molecular Phylogeny.

• Biological Technician, Dr. Peter Cattini lab, 02/01/23, 01/31/24, The effect of overeating and obesity on human pituitary growth hormone/placental lactogen production and activity in puberty and pregnancy.
• Research student (thesis based), Dr. Eftekharpour's lab, 01/01/20, 05/31/23, Role of Thioredoxin 1 in maintenance of nuclear lamina and cytoskeleton structure in context of neurodegenerative diseases.
• Research assistant, Dr. Eftekar Eftekharpour's lab, Department of Physiology and Pathophysiology, University of Manitoba, 09/01/19, 12/31/19
• Research assistant, Bioprocess and Fermentation Technology Laboratory, Department of Microbiology, University of Dhaka, 07/01/14, 11/30/15, Characterization of indigenous Bacillus thuringiensis strains based on their cry genes and Cry protein profile.

1. Jin, Y., Jarmasz, J. S., Sultana, S., Cordero-Monroy, L., Taylor, C. G., Zahradka, P., Kardami, E., & Cattini, P. A. (2024). Increased capacity to maintain glucose homeostasis in a transgenic mouse expressing human but not mouse growth hormone with developing high-fat diet-related insulin resistance, hepatic steatosis and adipose dysfunction. Journal of Molecular Endocrinology, 73(2), e240026. Retrieved Jul 19, 2024, from https://doi.org/10.1530/JME-24-0026

2. Islam, M. I., Sultana, S., Padmanabhan, N., Rashid, M. U., Siddiqui, T., Coombs, K., ... & Eftekharpour, E. (2024). Identification of Thioredoxin1 interacting proteins in neuronal cytoskeletal organization during autophagy. bioRxiv, 2024-02. Identification of Thioredoxin1 interacting proteins in neuronal cytoskeletal organization during autophagy (received minor revision in Biochimica et Biophysica Acta).

Manuscript under preparation

1. Txnip regulates ferroptosis through ferretinophagy. Nagakannan Pandian, Shakila Sultana, Md Imamul Islam, Eftekhar Eftekharpour.

Conference Papers

1. Shakila Sultana, Md Imamul Islam, Nirmala Padmanabhan, Tabrez Siddiqui, Eftekhar Eftekharpour. (2023). Linking oxidative stress to epigenetic changes. Manitoba Students Health Sciences Research Forum (Poster). Multiple award winner.

2. Nagakannan Pandian, Shakila Sultana, Md Imamul Islam, Eftekhar Eftekharpour. TXNIP promotes ferroptosis through NCOA4 mediated ferritinophagy. Canadian oxidative stress consortium 2023, Montreal (Poster).

3. Shakila Sultana, Md Imamul Islam, Eftekhar Eftekharpour. (2022). Downregulation of Trx1 is sufficient to induce neuronal laminopathy and alters DNA methylation reported in neurodegenerative diseases. Canadian Students Health Sciences Research Forum (Poster).

4. Shakila Sultana, Md Imamul Islam, Eftekhar Eftekharpour. (2022). Downregulation of Thioredoxin-1 is sufficient to induce neuronal laminopathy and molecular damage reported in neurodegenerative diseases. 15th Annual Canadian Neuroscience Meeting, Toronto (Poster).

5. Shakila Sultana, Tetiana Shcholok, Md Imamul Islam, Eftekhar Eftekharpour. (2021). Nuclear Laminopathy and oxidative stress in Alzheimer's Disease. 14th Annual Canadian Neuroscience Meeting 2021 (Online, Poster).

6. Shakila Sultana, Tetiana Shcholok, Chanhyuk Jin, Md Imamul Islam, Eftekhar Eftekharpour. (2021). Downregulation of Trx1 induces nuclear laminopathy and contributes to the pathophysiology of AD. Canadian Consortium on Neurodegeneration in Aging (CCNA) Science Day Poster Competition (Poster) won Best Poster award in Master’s category.