Sabyasachi Sarkar

Dynamic individual with hands-on experience in Enzymology and talent for navigating challenges. Brings strong problem-solving skills and proactive approach to new tasks. Known for adaptability, creativity, and results-oriented mindset. Committed to making meaningful contributions and advancing organizational goals.

• Postdoctoral researcher, University of California Berkeley, California Institute for Quantitative Biosciences, Berkeley, CA, 94720, Thiol-Reactive Photoactive Probes for the Site-Specific Heating of Proteins, Prof. Judith P. Klinman, 07/2023-present
• Graduate student, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, 208016, Studied multiheme enzymes, especially the diheme enzyme MauG, utilizing the synthetic analogs., Prof. S. P. Rath, 08/2015-05/2023

• Senior Research Fellow, Indian Institute of Technology Kanpur, 01/2017-05/2020
• Junior Research Fellow, Indian Institute of Technology Kanpur, 01/2015-05/2017

• Fast Protein Liquid Chromatography (Akta)
• UV-visible-NIR spectrophotometer (Perkin Elmer)
• Diode Array spectrophotometer with low temperature facility (Agilent, Unisoku)
• Fluorescence spectrometer (Perkin Elmer)
• GC-MS (Agilent)
• Glovebox (MBRAUN)
• IR spectrometer
• EPR spectrometer (Bruker)
• NMR (Jeol 500 MHz, 400 MHz)
• Mössbauer instrument (Wissel) with low temperature setup (JANIS)
• Cyclic voltameter (BASi Epsilon)
• Single crystal X-ray diffractometer (Bruker SMART APEX) equipped with CRYO Industries low-temperature apparatus.

• Protein Dynamics
• Biophysical Chemistry
• Biocatalysis
• Bioinorganic Chemistry

• SERB ITS Travel Grants, Awarded to attend the 16th European Biologic Inorganic Chemistry Conference (EuroBIC-16), July 17-21, 2022, Grenoble, hosted by University of Grenoble Alpes, France., 07/2022
• Qualified Graduate Aptitude Test in Engineering (GATE), 01/2014
• Qualified National Eligibility Test (NET) in Chemical Sciences, 01/2014

• Unravelling the Relaxation Pathway and Excited State Dynamics of Ruthenium(II) Polypyridyl Complexes Incorporating Phosphorus-Based Monodentate Ligands

      R Mishra, A Saha, P Chatterjee, S Kundu, M Verma, S Sarkar, S Sivakumar, A Dutta and A K Patra*

      Chem. Eur. J. (Just accepted)

• Probing Substrate Binding inside a Paramagnetic Cavity: A NMR Spectroscopy Toolbox for Combined Experimental and Theoretical Investigation

     S. Sarkar, C.-Q. Wu, S. Manna, D. Samanta, P. P.-Y. Chen* and S. P. Rath*

     Chem. Sci. 2024, 15, 17407.

• Unusual Stabilisation of Remarkably Bent Tetra-Cationic Tetra-radical Intermolecular Fe(III) μ-Oxo Tetranuclear Complexes

     S. Sarkar, R. K. Tiwari, D. Samanta, T. Guchhait, E. C. Sanudo, G. Rajaraman and S. P. Rath*

     Angew. Chem. Int. Ed. 2024, 63, e202402344.

• Binuclear Complexes with Single M-F-M Bridge (M: Fe, Mn, and Cu): A Critical Analysis of the Impact of Fluoride for Isoelectronic Hydroxide Substitution

     S. Sarkar, F. S. T. Khan, T. Guchhait and S. P. Rath*

     Coord. Chem. Rev. 2023, 479, 215003.

• Cooperativity in Diiron(III)porphyrin Dication Diradical-Catalyzed Oxa-Diels-Alder Reactions: Spectroscopic and Mechanistic Insights

     S. Sarkar, P. Sarkar, D. Samanta, S. K. Pati and S. P. Rath*

     ACS Catal. 2022, 12, 9589.

• Highly Oxidized Cobalt Porphyrin Dimer: Control of Spin Coupling via Bridge

      S. Sanfui, M. Usman, S. Sarkar, S. Pramanik, E. Garribba, and S. P. Rath*

      Inorg. Chem. 2022, 61, 8419.

• Long-Range Intramolecular Spin Coupling Through-Redox-Active Bridge Upon Stepwise Oxidations: Control and Effect of Metal Ions

      Y. A. Pandit, S. J. Shah, M. Usman, S. Sarkar, E. Garribba, and S. P. Rath*

      Inorg. Chem. 2022, 61, 5270.

• Ferromagnetic Coupling in Oxidovanadium(IV)–Porphyrin Radical Dimers

      A. K. Singh, M. Usman, S. Sarkar, G. Sciortino, D. Kumar, E. Garribba, and S. P. Rath*

      Inorg. Chem. 2021, 60, 16492.

• Stepwise Oxidations of Nickel(II)-Iron(III) Heterobimetallic Porphyrin Dimer: Structure, Spectroscopic and Theoretical Investigation

      A. Kumar, S. Banerjee, S. Sarkar and S. P. Rath*

     Dalton Trans. 2019, 48, 10089.

• Probing bis-FeIV MauG: Isolation of Highly Reactive Radical Intermediates

      T. Guchhait, S. Sarkar, Y. A. Pandit and S. P. Rath*

      Chem. Eur. J. 2017, 23, 10270.

• Cyclic Bisporphyrin Based Flexible Molecular Containers: Controlling Guest Arrangements and Supramolecular Catalysis by Tuning Cavity Size

      P. Mondal, S. Sarkar, and S. P. Rath*

      Chem. Eur. J. 2017, 23, 7093.

• Movies
• Music
• Travelling
• Cricket

• Diheme Enzyme MauG: Our Understanding towards Nature’s Design, S. Sarkar and S. P. Rath
• Research Scholars' Day, 08/14/2021, Kanpur, Uttar Pradesh, 208016, Covalent Attachment of Site Specific Photoactive-Heat Transfer Probes to Test Models of Long Range, Local Heating in Soybean Lipoxygenase, S. Sarkar, A. T. Iavarone and J. P. Klinman
• Bay Area Chemical Biology Symposium, 10/21-22/2024, Stanford, CA, Probing bis-FeIV MauG: Isolation of Highly Reactive Radical Intermediates, S. Sarkar, T. Guchhait and S. P. Rath
• 21st CRSI National Symposium in Chemistry (NSC-21), 07/14-16/2017, Hyderabad, Telangana, Probing bis-FeIV MauG: Isolation of Highly Reactive Radical Intermediates, S. Sarkar, T. Guchhait and S. P. Rath
• Research Scholars' Day, 11/09/2019, Kanpur, Uttar Pradesh, 208016, Best Poster Prize, Probing bis-FeIV MauG: From Electronic Communication to Reactivity, S. Sarkar, T. Guchhait and S. P. Rath
• 16th European Biologic Inorganic Chemistry Conference (EuroBIC-16), 07/17-21/2022, Grenoble, France

• Student Mentoring, UC Berkeley, Berkeley, CA, 94720, Mentored two undergraduate students in molecular biology, biophysical characterization and enzyme catalysis., 07/2023-ongoing
• Student Mentoring, IIT Kanpur, Kanpur, Uttar Pradesh, 208016, Mentored three master’s-project students in their senior thesis work on electronic communication, structure-property relationships and catalytic applications in synthetic diheme systems., 01/2017-05/2019