Navroop Dhaliwal

Experienced research scientist with 10 years of expertise in human stem cell technology and neuroscience. Skilled in utilizing advanced technology to generate and share valuable data for the scientific community. Collaborated with research teams from Sickkids Hospital, University of Toronto, and University of New Haven to improve research tools, protocols, and assays, contributing to significant scientific breakthroughs. Recognized for integrity and meticulous attention to detail in conducting complex research projects. Keen and fast learner, adept at adapting to any work setting.

Dhaliwal, N. K., Muffat, J., & Li, Y. (2024).mTORC1 and mTORC2 synergy in human neural development, disease and regeneration. Neural Regeneration Research. (Invited article and Accepted after review on October 12th2024).

Dhaliwal, N. K., Weng, O. Y., Li, Y. Protocol for efficient and inducible generation of CRISPR-Cas9 edited human cortical neurons from the iCas9-iNgn2 hPSCs. Star Protocols, https://doi.org/10.1016/j.xpro.2024.103352

Rosenstein, Aaron H. and Chai, Andrew and Sambathkumar, Rangarajan and Murareanu, Brandon M. and Dhaliwal, Navroop K. and Sun, Fumao and Zhao, Xinyaun and Dadvar, Abolfazl and Al-attar, Rasha and Gulati, Nitya and Yin, Ting and Nguyen, Maria and Serra, Danielle and Devina, Tania and Gandhi, Aanshi and Saleh, Mohammad and Gilbert, Penney and Laflamme, Michael A. and Ogawa, Shinichiro and Muffat, Julien and Li, Yun and Protze, Stephanie and Kunath, Tilo and Administrator, Sneak Peek and Garton, Michael, FAST-STEM: Synthetic Biology Toolkit for Next Generation Regenerative Medicine. July 24, 2024. Available at SSRN: https://ssrn.com/abstract=4903211 or http://dx.doi.org/10.2139/ssrn.4903211

Dhaliwal, N. K., Weng, O. Y., Dong, X., Bhattacharya, A., Ahmed, M., Nishimura, H., Choi, W. W. Y., Aggarwal, A., Luikart, B. W., Shu, Q., Li, X., Wilson, M. D., Moffat, J., Wang, L. Y., Muffat, J., & Li, Y. (2024). Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids. Cell reports, 43(5), 114173. https://doi.org/10.1016/j.celrep.2024.114173

Navroop Dhaliwal, Wendy W.Y. Choi, Julien Muffat & Yun Li. Modeling PTEN overexpression-induced microcephaly in human brain organoids. Mol Brain 14, 131 (2021). https://doi.org/10.1186/s13041-021-00841-3

Navroop K Dhaliwal. Synergistic hyperactivation of MTORC1 and MTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and brain organoids. Great Lakes Developmental Biology Symposium 2023, Toronto.

Navroop K Dhaliwal. Synergistic hyperactivation of MTORC1 and MTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and brain organoids. Developmental and Stem cell biology seminar series 2023, Sickkids, PGCRL Toronto.

Navroop K Dhaliwal. A novel in vitro platform for rapid generation of CRISPR

Knockout in pluripotent stem cell derived human neurons. Lightning talk at Development session in Ontario Cell Biology Symposium 2021, Virtual platform. 

Navroop K Dhaliwal, Kamelia Miri and Jennifer Mitchell. Nucleocytoplasmic transport of KLF4 mediated by ERK activation initiates exit of embryonic stem cells from naïve pluripotency. Nuclear Organization & Function meeting at Cold Spring Harbor Laboratory, NY in May 2016.

Navroop K Dhaliwal and Jennifer Mitchell. KLF4 nuclear export requires ERK activation and initiates exit from naive pluripotency. International Society of Stem Cell Research (ISSCR) 13th Annual meeting June 2015 in Stockholm.

• Garron Family Cancer Centre conference grant, 2000 CAD, 2023
• Axion Travel award, 500 USD, 2023
• Restracomp, Sickkids post-doctoral fellowship, 33750 CAD, 2020
• Canadian Council of University Biology Chairs (CCUBC) graduate student research prize, 2000 CAD, 2019
• Medicine by design conference grant, 2000 CAD, 2018
• CSB conference grant, 1000 CAD, 2016-2018
• Ontario Graduate Scholarship (OGS), 15000 CAD, 2013-2018
• University of Toronto Fellowship- OGS Top up, 1500 CAD, 2014-2018
• Elizabeth Ann Wintercorbyn Award, 500 CAD, 2014
• School of Graduate studies (SGS) conference grant, 620 CAD, Winter/Spring 2014
• University of Toronto Fellowship, 8100 CAD, Sep 2014 – Aug 2015
• Research Assistantship, 11205 CAD, Sep 2014 – Aug 2015
• University of Toronto Fellowship, 8000 CAD, Sep 2012 – Aug 2013

• Yun Li, PhD, Scientist, Hospital For Sick Children, 4168137654, yun.li@sickkids.ca, 686 Bay Street, Rm. 17.9709, Toronto, ON, M5G 0A4
• Jennifer Mitchell, PhD, Associate Professor, University of Toronto, (416)978-6711, ja.mitchell@utoronto.ca