Navita Sharma
Toronto,Canada
Summary
A dedicated post-doctoral fellow with extensive experience and passion for viral immunology research. An articulate Doctor of Philosophy in virology backed with master's in biotechnology with areas of keen interest: viral immunopathogenesis, therapeutic drug development, Host-pathogen interaction, Cellular pathways and Molecular biology.
Overview
6
6
years of professional experience
Work History
Post-doctoral Fellow
Department of Rheumatology, Toronto western hospital
01.2023 - Current
- Presently working as a post-doctoral researcher in the Department of Rheumatology at Toronto western hospital, University Health Network, Toronto with Dr. Vinod Chandran (University of Toronto) and Dr. Ali Abdul Sater (York University) in the project titled “TRAF1 a novel therapeutic target for the treatment of Psoriatic arthritis”. In this project I am determining the expression of an adaptor protein “TRAF1” in different immune subtypes of Psoriatic arthritis patient’s PBMCs and synovial fluid cells using spectral flow cytometry and investigating whether genetic manipulation of TRAF1 in psoriatic arthritis cells lowers their pro-inflammatory activation and cytokine production.
Research Associate
International center for genetic engineering and biotechnology (ICGEB)-Department of Biotechnology (DBT) BioCARe Processing and monitoring unit (PMU)
04.2022 - 12.2022
Research Associate
Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)
02.2022 - 04.2022
- Worked with Professor Alpana Sharma on the project titled “Delineating the anticancer potential and the mechanism of Unani medicinal formulation Itrifal-e-aftimoon in chronic myelogenous leukemia”
Scientific Consultant
Indian tuberculosis research consortium (ITRC) at Indian Council of Medical Research (ICMR) headquarters
11.2019 - 03.2020
- Worked in the therapeutics domain of Indian Tuberculosis research consortium, coordinating and administering all aspects of new and ongoing projects
Project Scientist
Centre for biomedical engineering, IIT Delhi
11.2018 - 08.2019
- Worked on the project titled “Artificial Skin (Bio-inspired Bi layer Polymeric Hybrid Scaffold) for Burn Injuries and Trauma Care (under IMPRINT Scheme)”.
Education
Ph.D. - Life Sciences
Bharathiar University
Coimbatore, India07.2019
Post Graduate certificate program (IPR) -
Global Institute of Intellectual Property Rights
Delhi, India08.2012
Master of Science - Biotechnology
Seedling Academy of Design Technology And Management, Jaipur
Jaipur, India06.2005
Bachelor of Science - Science
GD College
Alwar, Rajasthan, India06.2003
Skills
- Handling and processing of biological specimens like blood, serum, plasma, and synovial fluid
- Cell culture (primary cell culture of mouse peritoneal macrophages, human peripheral blood mononuclear cells, secondary culture of THP-1, Vero, C6/36, RAW 2647, L929 cell line etc)
- Virus isolation and propagation in various cell lines, Viral infectivity assay (Plaque assay)
- Sandwich ELISA assay, Multiplex assay
- Molecular biology techniques
- Flow cytometry (multiple parameter spectral flow cytometry)
- Animal handling of Balb/c mice, SD rats and albino wistar rats (worked on CFA induced arthritis model and second degree burn wound model)
- Professional competency in designing, execution, data analysis and reporting research results of the project
- Teaching experience
Accomplishments
· Awarded post-doctoral fellowship award from Arthritis Society Canada in 2022.
· Awarded gold medal of G. P. Talwar young scientist award at IMMUNOCON conference held in Visakhapatnam, India in 2017.
· Received Travel grant from Immunology society to attend IMMUNOCON conference held in Visakhapatnam.
· Qualified CSIR UGC (JRF) exam of 19 Dec 2011 with 19th rank
· Qualified GATE 2012 with 302 gate score in life sciences.
· Qualified CSIR UGC NET (LS) Exam of 19 June 2005.
· Qualified GATE 2007 with 377 gate score in life science
Languages
English, Hindi
English
Full Professional
Paperspublished
- Sharma N, Mishra KP, Chanda S, Bhardwaj V, Tanwar H, Ganju L, Kumar B, Singh SB (2019) Evaluation of anti-dengue activity of Carica papaya aqueous leaf extract and its role in platelet augmentation. Archives of Virology 164: 1095-1110
- Sharma N, Mishra KP, Ganju L & Singh SB (2018) Salidroside exerts Anti- Inflammatory Effect by Reducing Nuclear Factor κB and Nitric Oxide Produc tion in Macrophages. MedCrave Online Journal of Immunology 6: 1-8
- Sharma N, Mishra KP & Ganju L (2016) Salidroside exhibits anti-dengue virus activity by upregulating host innate immune factors. Archives of Virology 161: 3331-3344
- Mishra KP, Sharma N, Soree P, Gupta RK, Ganju L & Singh SB (2015) Hypoxia-Induced Inflammatory Chemokines in Subjects with a History of High- Altitude Pulmonary Edema. Indian journal of clinical biochemistry 31: 81-86
- Mishra KP, Sharma N, Diwaker D, Ganju L & Singh SB (2013) Plant de- rived antivirals: a potential source of drug development. Journal of Virology and Antiviral Research 2: 1-9
Postgraduatecertificateprograms
- Completed certificate Programme in “Current regulatory requirements for conducting clinical trials in India for investigational new drugs/new drug (version 3)” conducted by Clinical development services agency (CDSA) and SWAYAM portal in November 2021
- Completed certificate Programme in Intellectual property rights from Global Institute of Intellectual Property, Delhi in august 2012
Conferencesandworkshopsattended
- Presented research poster titled “TRAF1, a novel therapeutic target for the treatment of psoriatic arthritis” at the Annual Ogryzlo research day 2024 University of Toronto, Toronto on 25 June 2024
- Presented research poster titled “TRAF1, a novel therapeutic target for the treatment of psoriatic arthritis” at the Krembil research day 2024, Krembil discovery tower, Toronto on 11 April 2024
- Participated in “Good Clinical Practice- Orientation workshop” held at Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi on December 04, 2019 organized by Clinical development services agency (CDSA) THSTI Ministry of Science and technology, government of India
- Selected to attend Science Communication Workshop organized by Wellcome trust DBT INDIA alliance on 7-8 September 2017 in New Delhi
- Presented research paper titled ‘Salidroside inhibits dengue virus protein synthesis by up regulating eIF-2α phosphorylation and host innate immune factors’ for G.P. Talwar young scientist award at IMMUNOCON 2016 held in Visakhapatnam, from 16 feb- 18 feb 2017
- Presented research paper titled ‘Evaluation of anti-dengue activity of Carica papaya aqueous leaf extract and its role in platelet augmentation’ at International Congress of Immunology held in Melbourne, Australia, from 21-26 august 2016
- Presented research paper titled ‘Novel Antiviral Activity of Salidroside against Dengue Virus Serotype 2’ at FIMSA held in Singapore from 30 june -3 july 2015
References
- Dr. K.P. Mishra, Scientist ‘F’, Defence Institute of Physiology and allied Sciences, DRDO, Delhi India, kpmdipas@gmail.com
- Dr. Vinod Chandran, Associate Professor, Division of Rheumatology, Department of Medicine, University of Toronto, Vinod.chandran@uhn.ca
- Dr. Ali abdul Sater, Associate Professor, Faculty of Health - School of Kinesiology & Health Science, York University, Toronto, Ontario, Canada, aasater@yorku.ca
Timeline
Post-doctoral Fellow
Department of Rheumatology, Toronto western hospital
01.2023 - Current
Research Associate
International center for genetic engineering and biotechnology (ICGEB)-Department of Biotechnology (DBT) BioCARe Processing and monitoring unit (PMU)
04.2022 - 12.2022
Research Associate
Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)
02.2022 - 04.2022
Scientific Consultant
Indian tuberculosis research consortium (ITRC) at Indian Council of Medical Research (ICMR) headquarters
11.2019 - 03.2020
Project Scientist
Centre for biomedical engineering, IIT Delhi
11.2018 - 08.2019
Ph.D. - Life Sciences
Bharathiar University
Post Graduate certificate program (IPR) -
Global Institute of Intellectual Property Rights
Master of Science - Biotechnology
Seedling Academy of Design Technology And Management, Jaipur
Bachelor of Science - Science
GD College
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