Mathew Smith
San Ramon
Summary
Skilled research associate with eight years of laboratory work. Demonstrates strong focus on team collaboration and achieving measurable outcomes. Adaptable with changing needs, ensuring reliability and consistent performance. Proficient in laboratory techniques, including PCR and QC applications.
Overview
5
5
years of professional experience
Work History
Senior Research Associate
Abiosciences, Inc.
03.2023 - 07.2025
- Performed routine cell/tissue processing and NGS library preparation using 10x Genomics protocols (Chromium Single Cell and Visium Cytassist/HD)
- Sectioned FFPE tissue and affixing sections to slides to carry into downstream processes, including H&E staining and imaging using EVOS m7000 Imaging System
- Regular library QC and pooling using Qubit Fuorometer
- Some bioinformatics analysis through 10x Genomics Loupe Browser
- Generating reports summarizing laboratory work and QC for clients
Research Associate
Loop Genomics
07.2021 - 02.2023
- Performed Routine NGS library preparation and pooling
- Carried out regular QC duties using qPCR, Qubit fluorometry, and a Tecan microplate reader
- Acted as co-head of manufacturing operations, performing kit formulation, QC, and packaging assembly
- Prepared sequencing runs and operated Illumina NextSeq
Formulation Scientist I
Thermo Fisher Scientific
09.2020 - 06.2021
- Using batch formulation techniques and qPCR to determine concentrations of resuspended MS2 phage
- Collaborated with other formulation scientists to prepare bulk formulations of MS2 phage to be distributed for SARS-CoV-2 in-vitro diagnostics
- Filled out and verified batch records
- Performed In-vitro diagnostic assay QC using qPCR
Education
Master of Science - Biological Sciences
Louisiana State University
Baton Rouge, LA05.2020
Bachelor of Science - Biological Sciences, Chemistry
California State University, Stanislaus
Turlock, CA05.2015
Skills
- NGS library preparation
- PCR
- Nucleic acid purification and quantification
- Statistical analysis with Excel
- High-throughput pipetting
- Technical presentations
- Technical writing
- Effective multitasking
- Documentation and reporting
Publications
- “Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cells.” eLife, 2024
- “DNA damage regulates direct association of TOR kinase with the RNA polymerase-II transcribed HMO1 gene DNA damage regulates direct association of TOR kinase with the RNA polymerase-II transcribed HMO1 gene.” Molecular Biology of the Cell, 2017
- “Cerebratulus lacteus ribosomal protein S29 mRNA, partial cds Cerebratulus lacteus ribosomal protein S29 mRNA, partial cds.” NCBI, 2014
Timeline
Senior Research Associate
Abiosciences, Inc.
03.2023 - 07.2025
Research Associate
Loop Genomics
07.2021 - 02.2023
Formulation Scientist I
Thermo Fisher Scientific
09.2020 - 06.2021
Master of Science - Biological Sciences
Louisiana State University
Bachelor of Science - Biological Sciences, Chemistry
California State University, Stanislaus
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