SAMI AYACHI
Montréal
Summary
Innovative scientist and clinical research leader with a Ph.D. in biochemistry and molecular genetics, with over 10 years of expertise in molecular diagnostics, pediatric oncogenomics, and clinical research operations. Proven success in coordinating multi-site trials, leading cross-functional teams, and publishing in high-impact journals. Expertise in integrating advanced genomic research with clinical trial execution to expedite drug development processes. Recognized for driving precision medicine initiatives, ensuring regulatory compliance, and translating complex data into actionable insights that enhance patient outcomes. Experienced with coordinating clinical trials and managing study logistics. Utilizes comprehensive knowledge of research protocols to ensure compliance and accuracy. Track record of fostering effective team collaboration and maintaining precise documentation throughout research process.
Overview
5
5
years of professional experience
Work History
Clinical Research Coordinator
Centre Hospitalier de l’Université de Montréal (CHUM)
01.2024 - Current
- Lead and manage a clinical research team of 8, optimizing workload distribution, staff development, and project delivery.
- Oversee a multi-site study integrating HIV prevention and HCV care for vulnerable populations (target: 500 patients).
- Ensure full compliance with ethical guidelines, patient confidentiality, and regulatory standards.
- Coordinate data collection, conduct analyses, and prepare manuscripts for submission to peer-reviewed journals.
- Develop abstracts and presentations for international conferences, positioning CHUM as a leader in infectious disease research.
Molecular Biology & Pediatric Onco-Genomics Specialist
Hôpital Sainte-Justine
01.2022 - 01.2024
- Directed molecular diagnostics for pediatric oncology cases (8–10 per week), identifying actionable genetic alterations.
- Led tumor profiling using advanced NGS pipelines (exome, transcriptome, WGS) to guide treatment decisions.
- Coordinated AML research project analyzing genomic data from 320 patients, identifying key susceptibility mutations.
- Integrated deep sequencing into MRD analysis, enabling earlier detection of subclonal mutations post-treatment.
- Presented complex sequencing reports to clinical teams, supporting precision oncology decisions.
Molecular Diagnostics Specialist
Hôpital Maisonneuve-Rosemont – OPTILAB-CHUM
01.2021 - 01.2022
- Performed and validated molecular diagnostic tests in GLP-certified laboratories.
- Repatriated key hematological assays (MDS/MPN) from external labs (Mayo Clinic) to Quebec, using a 141-gene AML panel.
- Partnered with INESSS to assess sequencing methods for IDH1/IDH2 mutations.
- Authored SOPs and analysis protocols, ensuring quality, accuracy, and compliance.
Education
Ph.D. - Biochemistry – Molecular Genetics
Université de Montréal
Montréal, QC01.2022
M.Sc. - Biochemistry
Université de Montréal
Montréal, QC01.2014
M.Sc. - Biochemistry
Badji Mokhtar University
Jazair01.2009
B.Sc. - Biochemistry
Badji Mokhtar University
Jazair01.2007
Skills
- Clinical Research & Trial Coordination (Phases I–III)
- Genomics & Molecular Diagnostics (NGS, Exome, Transcriptome, WGS)
- Translational & Precision Medicine Strategy
- Regulatory Compliance & Research Ethics (GLP, CAP/CLIA)
- Data Analysis, Biostatistics & Manuscript Development
- Cross-Functional Leadership & Stakeholder Engagement
- Oncology & Hematology Therapeutic Expertise
- Publication & Conference Presentation Strategy
- Good clinical practices
- Electronic data capture
- Documentation management
- Informed consent
- Adverse event reporting
- Study protocols
- Patient recruitment
- Data analysis
- Informed consent process
- Research sops understanding
- Clinical trial management
- Trial management
- Protocol development
- Data collection techniques
- Specimen collections
- Participant screening
- Records maintenance
- Laboratory results management
- Analytical thinking
- Disease research
- Leadership skills
Languages
French
Full Professional
English
Full Professional
Awards
Awards: Tuition Exemption Grant (Embassy of Algeria, 2015), Best PhD Poster Presentation (HMR Research Day, 2015).
Publications
- Multiple peer-reviewed publications, including Experimental Hematology (2020) and Blood Advances (2023).
- Abstracts submitted to Leukemia and international conferences.
Timeline
Clinical Research Coordinator
Centre Hospitalier de l’Université de Montréal (CHUM)
01.2024 - Current
Molecular Biology & Pediatric Onco-Genomics Specialist
Hôpital Sainte-Justine
01.2022 - 01.2024
Molecular Diagnostics Specialist
Hôpital Maisonneuve-Rosemont – OPTILAB-CHUM
01.2021 - 01.2022
M.Sc. - Biochemistry
Université de Montréal
Ph.D. - Biochemistry – Molecular Genetics
Université de Montréal
M.Sc. - Biochemistry
Badji Mokhtar University
B.Sc. - Biochemistry
Badji Mokhtar University
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