Summary
Overview
Work History
Education
Skills
Websites
Languages
Timeline
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Loïc VALADE

Loïc VALADE

Montréal,QC

Summary

Organic chemist from France with a diverse set of experiences, currently working in Canada for a CRO in pharmaceutical chemistry. Currently looking to deepen his exploration of chemistry in North America.

Overview

5
5
years of professional experience

Work History

Associate Scientist

Paraza Pharma
10.2022 - Current
  • Results driven SAR study involving multi-step asymmetric synthesis of biologically active compound for 1.5 years with a U.S based biotech client
  • Synthesis and characterization of low M.W compounds following design ideas using synthetic tools to achieve, including polar moieties such as chiral lactam, chiral diacid, unnatural amino acids, Design propositions based on in vitro / in vivo biological data and crystal structures (CADD)
  • Development of reaction conditions to ensure quick SAR study (40+ compounds/months) Weekly update reporting results and bi-Weekly Zoom presentations to client and higher management
  • Routine maintenance and troubleshooting of common lab equipment, SOP edition and application, training issued to new employees
  • Oversaw new lyophilizer installation and start-up.

Internship in MACO group

IPCM
02.2022 - 05.2022
  • 6 months internship in Paris (France) Subject : Synthesis of new silylated diazenes for catalytic C-H silylation reaction
  • Synthesis of water and oxygen sensitive silylated diazenes using glove-box methods and Schlenck technique for bench chemistry
  • Vacuum distillation and traditional distillation
  • Results : Synthesis and characterization of new tri-alkylsilyl diazenes with short conditions optimization for catalytic C-H silylation, synthesis and characterization of new alkoxysilyl diazenes further used for improved methodology.

Master 1 Internship

ICBMS
05.2020 - 08.2020
  • Synthesis and characterization of fluorous-tag carbohydrates
  • Synthesis and usage of fluorous capped silica for fluorous solid-phase extraction

Internship and tutoring

Université Savoie Mont Blanc
01.2019 - 01.2020
  • Bibliographical review on chemical and physical resistance of processed graphite for sealing applications in nuclear water-cooling system for a private company
  • Tutoring in basic organic chemistry to 1st year Bachelor student, up to 35 students per tutoring.

Education

Master 2 -

Sorbonne Universités

Master 1 -

Université Claude Bernard

Bachelor in chemistry -

Université Savoie Mont-Blanc

Skills

  • Experience in CRO
  • English/French environment
  • Small size team experience (
  • Lab Scheduling
  • Scientific Methodologies
  • Multi-step synthesis
  • Asymmetric synthesis
  • Organometallic chemistry
  • Anaerobic chemistry
  • Anhydrous chemistry
  • Glovebox as a main workspace
  • NMR analysis, 1D, 2D
  • Vacuum distillation
  • Preparative-HPLC (reverse phase)
  • Flash purification (normal and reverse phase)
  • Microwave reactors
  • Office 365 Suite
  • Chemdraw
  • MNova
  • Vortex
  • Maestro
  • Dotmatics
  • Findmolecules
  • MassLynx
  • SciFinder
  • Reaxys

Languages

French
Native or Bilingual
English
Full Professional

Timeline

Associate Scientist

Paraza Pharma
10.2022 - Current

Internship in MACO group

IPCM
02.2022 - 05.2022

Master 1 Internship

ICBMS
05.2020 - 08.2020

Internship and tutoring

Université Savoie Mont Blanc
01.2019 - 01.2020

Master 2 -

Sorbonne Universités

Master 1 -

Université Claude Bernard

Bachelor in chemistry -

Université Savoie Mont-Blanc

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Loïc VALADE