KUN LIU
Burnaby,Canada
Summary
Broad expertise in bioconjugation chemistry, oligonucleotide chemistry, and oligonucleotide-protein bioconjugation techniques
Overview
11
11
years of professional experience
Work History
Postdoctoral Fellow
University of British Columbia
11.2021 - Current
- Modified nucleotides synthesis, purification and characterization
- SELEX for chemically enhanced DNAzymes as a novel coupling strategy for creating antibody-drug conjugates
- Whole-animal SELEX for chemically enhanced aptamer targeting PSMA
- Radiolabelling of aptamer for in vivo imaging
- 3 Papers in manuscript preparation
Associate Research Fellow
Metabolic Insights
11.2020 - 10.2021
- Synthesis, purification, and characterization of oligonucleotide-antibody conjugates for the development of an electrochemical insulin biosensor
PhD Candidate
Simon Fraser University
09.2013 - 06.2021
- In vitro selection for aptamer targeting Troponin I
- In vitro selection of DNAzymes as a novel bioconjugation method
- Utilizing the DNAzyme for bioconjugation and sensing
Education
PH.D. - BIOCHEMISTRY
Simon Fraser University
Burnaby, BC06-2021
MASTER OF SCIENCE - CHEMISTRY
Tsinghua University
Beijing, China06.2011
Skills
- Research procedures
- Modified nucleotide synthesis
- In vitro selection for aptamer/DNAzyme
- Oligonucleotide fictionalization and purification
- Oligonucleotide-protein bioconjugation
- HPLC, BLI, ELISA, SDS-PAGE
Accomplishments
Won 2023 Prostate Cancer Foundation Canada Grant-in-Aid competition award
Publications
- Liu, K.; Liu, F.; Zhang, N.; Liu, S.; Jiang, Y. Int. J. Mol. Sci., 2012, 13, 5818-5831.
- Liu, K.; Lat, P. K.; Yu, H.-Z.; Sen, D. NAR. 2020, 48, 13, 7356–7370.
- Liu, K.; Shen K.; Yu, H.-Z.; Sen, D. Electrochim. Acta. 2021, 379, 138125-9.
- Gan, N.; Liu, K.; Qi, L.; Zhang, G.; Guo, Y.; Sen, D.; Yu, H.-Z. J. Phys. Chem. C., 2020, 124, 35, 19083–19090.
- Lat, P. K.; Liu, K.; Kumar, D. N.; Wong, K. K. L.; Verheyen, E. M.; Sen, D. NAR. 2020, 48, 10, 5254–5267.
- Gao, X.; Qi, L.; Liu, K.; Meng, C.; Li, Y.; Yu, H.-Z. Anal. Chem. 2020, 92, 9, 6229–6234.
- Leung, T. Y.; Lin Q.; Liu, K.; Sen. D.; Yu, H.-Z. Langmuir. 2024, , 40, 39, 20576–20583.
LinkedIn Profile
https://www.linkedin.com/in/liu-kun-71105bba/
Timeline
Postdoctoral Fellow
University of British Columbia
11.2021 - Current
Associate Research Fellow
Metabolic Insights
11.2020 - 10.2021
PhD Candidate
Simon Fraser University
09.2013 - 06.2021
PH.D. - BIOCHEMISTRY
Simon Fraser University
MASTER OF SCIENCE - CHEMISTRY
Tsinghua University