KEYVAN SEDAGHAT

Innovative pharmacology and biomedical sciences educator with a PhD in Cellular and Molecular Medicine. Demonstrated leadership in scientific collaborations and curriculum development that enhance student learning outcomes. Expertise in translating complex pharmacological concepts into accessible, evidence-based educational materials.

• Journal Articles
• Hajatdoost L, Sedaghat K, Walker EJ, Thomas J, Kosari S. (2018). Chemotherapy in Pancreatic Cancer: A Systematic Review. Medicina, 54(3).
• Sedaghat K, Tiberi M. (2011). Cytoplasmic tail of D1 dopaminergic receptor differentially regulates desensitization and phosphorylation by G protein-coupled receptor kinase 2 and 3. Cell Signaling, 23(1), 180–192.
• Sedaghat K, Nantel M-F, Ginsberg S, Lalonde V, Tiberi M. (2006). Molecular characterization of dopamine D2 receptor isoforms tagged with green fluorescent protein. Molecular Biotechnology, 34(1), 1–14.
• Jackson A, Sedaghat K, Minerds K, James C, Tiberi M. (2005). Opposing effects of phorbol-12-myristate-13-acetate on structurally related human dopamine D1 and D5 receptors. Journal of Neurochemistry, 95(5), 1387–1400.
• Books & Chapters
• Sedaghat K, Zhang B, Yang X, Lefebvre C, Tiberi M. (2015). Study of Dopamine D1 Receptor Regulation by G Protein-Coupled Receptor Kinases Using Whole-Cell Phosphorylation and Cross-Linking Methods. In Dopamine Receptor Technologies, Neuromethods, Vol. 96, Humana Press.
• Momeni T, Sedaghat K. (2000). Chlorophyll and Its Stability. Iranian Research Institute of Forests and Rangelands.

• Doctoral Researcher | University of Ottawa / Ottawa Health Research Institute (OHRI) (Ottawa, Ontario) 2002 – 2008
• Investigated molecular mechanisms regulating dopamine D1 receptors by G protein-coupled receptor kinases GRK2 and GRK3.
• Studied receptor phosphorylation, desensitization, intracellular sorting, cellular signaling, and receptor-protein interactions.
• Conducted cell-based and molecular experiments and authored peer-reviewed publications and international scientific presentations.
• Trained and supervised postdoctoral fellows, graduate students, and summer students; coordinated the OHRI Summer Student Program in 2006 and 2007.

• Editorial Board Member & Peer Reviewer | Elsevier Publishing
• Contribute scientific expertise to the review and evaluation of scholarly publications, supporting research quality and scholarly communication.

• Best Poster Presentation Award, Pharmacological Society of Canada — Great Lakes GPCR Retreat (2007)
• Second Prize, Best Oral Presentation — Ottawa Health Research Institute Research Day (2004)
• Best Basic Sciences Poster Presentation — University of Ottawa Department of Psychiatry Research Day (2004)
• Presented research at Gordon Research Conferences, Experimental Biology, Society for Neuroscience, Great Lakes GPCR Retreat, and OHRI research programs.
• Invited presentations on hand hygiene, infection prevention, and healthcare safety.

• International Society for Neurochemistry (ISN)
• ASPET
• British Pharmacological Society (BPS)
• American Chemical Society (ACS)
• Iranian Neuroscience Society (INS)