Isabella Monaghan Chow

As an undergraduate student completing my Honours specialization in Biochemistry and Pathology of Human Disease, I am eager to transition into a research-based Master's program that aligns with my academic and research goals. With a solid foundation in biochemical principles and pathology, as well as research experience within three separate labs over the past 4 years, I bring hands-on laboratory experience. I am particularly interested in science as it applies to psychiatry, mental and behavioral sciences, and I am excited about the opportunity to engage in advanced research under the supervision of any of the esteemed faculty members. Due to my past laboratory experience I possess excellent critical thinking and reasoning skills as well as a knowledge of research methodology and laboratory techniques. Seeking admission to U of Ts Master's program I am confident that my academic background and research experience make me a strong fit.

• CReATe Fertility and Research Center, 2021-2023- Conducted research on mothers undergoing IVF treatment. Detected and analyzed the combination of mutations in factors of the clotting cascade between the mother and the fetus that puts the fetus at risk for spontaneous abortion under the supervision of Dr. Svetlana Madjunkova.

• Martin Duennwald Lab, 2022-2023- Conducted research on the neurodegenerative disease of Parkinson's under the supervision of Dr. Martin Duennwald. Looked at the various mutations of the protein alpha-synuclein in a yeast model system and analyzed their impact on cell growth, protein localization, and protein concentration.

• Matthew Mailing Transplant Center, University Hospital, London ON, 2023-present- Conducted research focusing on the circular RNA circCRIM1 in relation to cardiovascular disease, specifically ischemia-reperfusion injury. Helped discover a new isoform of circCRIM1 present solely in cardiac tissue and determined it's level of expression in response to cellular injury in cardiomyocyte cell lines. Detected level of expression of circCRIM1 within human and mice cardiomyocyte cell lines as well as in various mice tissues of major transplant organs.

• Sunnybrook Hospital, 2023-present- Volunteering in the Radiology department to help patients with any questions they may have and delivering requisitions to physicians

• Sick Kids, 2018- Taking care of children with 22q syndrome

• Youth Opportunities Unlimited, 2022-present- Aiding in the food bank for underprivileged or homeless youths of London Ontario

• Tutor, Notre Dame High School, 2017-2020- Tutor in physics, chemistry, biology and french

• Volunteer swim coach, 2018- Aided in coaching children with both mental and physical disabilities

• Canadian Blood Services
• Lifesaving Society Ontario
• Medical Science Community Outreach Program
• Canadian Red Cross