Summary
Overview
Work History
Education
Skills
Award
Pulishcation
Timeline
Generic

DUC TIN TRAN

Toronto,ON

Summary

I had a total of over eight years working in an immunology, and cell biology research environment, and diverse animal model hands-on experiences. I was completely aware of the way to design, execute, and interpret experiments, and how to write and optimize the new protocol. Experience in finding a new method to contribute to project development. Greatly co-operate with other departments to accomplish the projects. I self-developed the ability to learn effectively and adapted well to rising situations. I possessed the ability to concentrate on individual tasks, and also contribute to developing the overall research goals of the laboratory. I am interested in new test method development and troubleshooting. Hardworking Postdoctoral Research Fellow with a demonstrated record of research success. Self-directed and motivated professional with a highly-ethical, meticulous, and thorough approach.

Overview

12
12
years of professional experience

Work History

Postdoctoral Research Fellow

St.Michael's Hospital
09.2022 - Current
  • Developed unique research into heart disease, renal disease and Diabetes models (cardiac hypertrophy, UUO and IRI).
  • Designed research projects and alternative approaches and discussed results with professor.
  • Maintained accurate records of research findings and provided statistical analysis of data results.
  • Authored professional scientific papers for publishing in peer-reviewed journals.
  • Contributed to and actively participated in research conception, design and execution to address defined problems.

Ph.D. Researcher

Chonnam National University And Hospital
03.2015 - 08.2021
  • Designed, executed experiments and work under minimal supervision of supervisor to complete the projects:
  • Created new sepsis model: Persistent Inflammation, Immunosuppression, and Catabolism Syndrome
  • Examined Anti-inflammatory and Immunomodulatory roles of bilirubin in “two-hit” sepsis models
  • Investigated the effect anti-inflammatory agents (such as BMS-470539, bilirubin, curcumin, astaxanthin and Avenanthramide C) on lipopolysaccharide-induced human neutrophil activation
  • Monitored the process of projects, and ordered materials
  • Recommended and optimized the new protocols, made scheduled work, and wrote the report weekly for the supervisor
  • Proficiency used the immunology assay and cells assay (Primary and Stem cell culture, flow cytometry, PCR, ELISA, western blotting, Luminex assay)
  • Advanced manipulation in testing mouse model (such as including subcutaneous, intra-peritoneal and intravenous injections, blood and tissue collection)

Researcher

Saigon High Tech Ho Chi Minh
08.2013 - 02.2015
  • Wrote the development and test plan medical devices such as New PRP pro Kit, ADSC extraction kit and skincare product line.
  • Reported and recommended the solution to improve the product quality
  • Co-operated QA and QC to test and evaluate the products
  • Trained the clients, researcher and sale staffs about the manipulations to isolate Platelet Rich Plasma (PRP) and mesenchymal stem cell (MSC) by kit, the application of PRP and stem cell in pre-clinical and clinical research.

Trainee

VietNam Stem Cell Institute
08.2012 - 07.2013
  • Isolating the bone marrow mouse-derived mesenchymal stem cells
  • Isolating the human adipose tissue-derived mesenchymal stem cells
  • Differentiated the adipose tissue-derived mesenchymal stem cells into hepatocytes by mouse liver extraction and chemical
  • Involved in making the cirrhosis mouse model by CCl4

Education

Ph.D. - Biomedical Sciences

Chonnam National University And Hospital
Gwangju, South Korea
08.2021

Bachelor of Science - Biotechnology

University of Sciences, Vietnam National University Ho Chi Minh City
Ho Chi Minh City, Vietnam
10.2013

Skills

  • Organization and Making a Plan
  • Technical analysis (Microsoft Office, ImageJ, GraphPad Prism)
  • Animal models (sepsis, TAC, UUO, IRI)
  • Detail-oriented
  • Write the academic articles and protocol or instructions
  • Troubleshooting
  • Cells-based Bioassay (flow Cytometry, PCR, ELISA, Western blotting, Luminex Assay, Immunostaining,)
  • Proficiency in cell handling (stem cells, HK2 cells, fibroblast cells, vascular smooth muscle cells, cardiomyocytes,)

Award

03/2015-09/2017- Scholarship from Brain Korea 21 Grant for Graduate Researcher (Korea Government funding).

10/2017-08/2019-Scholarship from National Research Foundation of Korea, Graduate School of Medical Sciences, Chonnam National University sponsor for graduate student (position Research Assistant).

07/2023-06/2024-Novo Nordisk-BBDC Postdoctoral Fellowship from Banting and Best Diabetes Centre.

07/2024-06/2025-Novo Nordisk-BBDC Postdoctoral Fellowship from Banting and Best Diabetes Centre.

Pulishcation

1.Tran DT, Batchu SN, Advani A. Interferons and interferon-related pathways in heart disease. Front Cardiovasc Med. 2024 Apr 11;11:1357343. doi: 10.3389/fcvm.2024.1357343. PMID: 38665231; PMCID: PMC11043610.

2. Hong LYQ, Yeung ESH, Tran DT, Yerra VG, Kabir MDG, Advani SL, Liu Y, Batchu SN, Advani A (2023) Altered expression, but small contribution, of the histone demethylase KDM6A in obstructive uropathy in mice. Disease Models and Mechanisms, 16, dmm049991. Impact Factor 4.3

3. Yerra VG, Batchu SN, Kaur H, Kabir MDH, Liu Y, Advani SL, Tran DT, Sadeghian S, Sedrak P, Billia F, Kuzmanov U, Gramolini AO, Qasrawi DO, Petrotchenko EV, Borchers CH, Conelly KA, Advani A (2023) Pressure overload induces ISG15 to facilitate adverse ventricular remodeling and promote heart failure. Journal of Clinical Investigation, 133, e161453. Impact Factor 15.9

4. Kaur H, Yerra VG, Batchu SN, Tran DT, Kabir MDG, Liu Y, Advani SL, Sedrak P, Geldenhuys L, Tennankore KK, Poyah P, Siddiqi FS, Advani A (2023) Single cell G-protein coupled receptor profiling of activated kidney fibroblasts expressing transcription factor 21. British Journal of Pharmacology, 180, 2898-2915. Impact Factor 7.3

5. Tran DT, Jeong YY, Kim JM, Bae HB, Son SK, Kwak SH (2020) The anti-inflammatory role of bilirubin on "two-hit" sepsis animal model. International Journal of Molecular Sciences, 21, 8650. Impact Factor 5.6

6. Lee S, Ju W, Tin TD, Kim J, Lee JS, Park CH, Kwak SH (2020) Effect of BMS-470539 on lipopolysaccharide-induced neutrophil activation. Korean Journal of Anesthesiology, 73, 151-157. Impact Factor 2.9

7. Cho KB, Park CH, Kim J, Tin TD, Kwak SH (2020) Protective role of curcumin against lipopolysaccharide-induced inflammation and apoptosis in human neutrophils. Anesthesia and Pain Medicine (Seoul), 15, 41-48.

8. Jang EA, Kim JY, Tin TD, Song JA, Lee SH, Kwak SH (2019) The effects of BMS-470539 on lipopolysaccharide-induced acute lung injury. Acute and Critical Care, 34, 133-140. Impact Factor 1.6

9. Chung SY, Kim J, Bae HB, Tin TD, Ju W, Kwak SH (2018) The effects of flecainide acetate on inflammatory-immune response in lipopolysaccharide-stimulated neutophils and on mortality in rats. Acute and Critical Care, 33, 34-41. Impact Factor 1.6

Timeline

Postdoctoral Research Fellow

St.Michael's Hospital
09.2022 - Current

Ph.D. Researcher

Chonnam National University And Hospital
03.2015 - 08.2021

Researcher

Saigon High Tech Ho Chi Minh
08.2013 - 02.2015

Trainee

VietNam Stem Cell Institute
08.2012 - 07.2013

Ph.D. - Biomedical Sciences

Chonnam National University And Hospital

Bachelor of Science - Biotechnology

University of Sciences, Vietnam National University Ho Chi Minh City
DUC TIN TRAN