Bonaventure C. Obi

· Hands-on experience in bioassay-guided screenings of bioactive constituents for antidiabetic, antioxidant, anticancer, and immunomodulatory activities.

· Cellular studies using cell culture techniques and expertise in laboratory animal handling and models.

· Antiproliferative studies in cancer cell line (Caco-2) (test for cell viability and cytotoxicity).

· Preisolation analyses of crude extracts and fractions from different natural sources.

· Exposure to isolation and identification of bioactive compounds using biochemical laboratory instrumentation such as spectroscopic techniques (UV-visible, H-NMR, 13C-NMR) and microplate-based ultra-sensitive in vitro assays.

· Nanoformulation and drug delivery systems for conventional drugs and phytopharmaceuticals, pharmacokinetics/pharmacodynamics and biopharmaceutical evaluations,

· Hands-on experience in clinical studies in humans.

· Very strong interpersonal and communication skills

· Ability to convey complex technical information verbally and in writing.

· Excellent interpersonal and supervisory skills.

· Organization skills- Technical-Chair, & member, ad-hoc faculty committee on academic conferences and workshops.

· Member, departmental examination board.

· Departmental ICT officer.

· Academic writing and publications.

· Grant Writing.

· Ability to multitask with a high degree of accuracy.

• Extra-curricular activity - football, lawn tennis, volleyball and music.

· Collaborated with a team of six (6) in developing a grant proposal - Nanotheranostic formulation of kaurenoic acid for effective target delivery in breast and prostate cancer treatment and determination of the mechanism of action. National Research Fund (NRF). (Awarded– Tertiary Education Fund, TETFund, Nigeria), (TETFund/DR&D/CE/NRF/STI/47/2019/VOL.I).

· Grant funding for Academic Staff Training and Development (AST&D) intervention in support of my postgraduate (PhD) research project at the University of Ottawa, Ontario, Canada. (Awarded –TETF/DASTD/UNIV/ENUGU/TSAS/2020/VOL.I).

· Collaborated with a team of twelve (12) in developing a grant proposal - Development of nanoformulated astonine and akiluvir (GB-1) as potent inhibitors against SARS-CoV-2 infection. (Submitted for evaluation)

• • Nigerian Institute of Management (Chartered) • West African Society for Pharmacology (WASP) • West African Network for Natural Products Research Scientists (WANNPRES). • Society for Medicinal Plant and Natural Product Research (GA) •

· Safe use of Autoclaves, 2023

· Respect in the Workplace Training & Certification, 2022

· Worker Health and Safety Awareness Training & Certification 2022

· Workplace Hazardous Materials Information System (WHMIS 2015) Training & Certification 2022

· Proficiency Cert. in Advanced Digital Appreciation 2022

· Proficiency Certificate in Management (chartered) 2011

· BC Obi, TC Okoye, VE Okpashi, CN Igwe, EO Alumanah (2016). Comparative study of the antioxidant effects of metformin, glibenclamide, and repaglinide in alloxan-induced diabetic rats. Journal of Diabetes Research Volume 2016, Article ID 1635361.

· Obi BC, Okoye TC, Joshua PE, Onyeto CA, Alumanah EO (2015). Comparative study of the antidiabetic and biochemical effects of metformin, glibenclamide and repaglinide in alloxan-induced diabetic rats. Afr J Pharm Pharmacol; 9:1026-36.

· FN Mbaoji, CA Onyeto, OO Ndu, BC Obi, AM Onwuka (2020). Anti-hyperglycemic effects of Stemonocoleus micranthus (Fabaceae) stem bark on alloxan-induced hyperglycemic rats. Journal of Medicinal Plants Research. 15(4):140-149

· A Ibezim, BC Obi, MN Oforkansi, CJ Mbah, and NJ Nwodo (2018). Discovery of trypanocidal bioactive leads by docking study, molecular dynamic simulation and in vivo screening. ChemistrySelect 3:2386– 2389.

· Akunne TC, Ilogu LC, Obi BC, Akah PA (2017). Protective effects of Buchholzia coriacea seeds extract and fractions on blood glucose and hyperlipidemia in diabetic rats. Int J Basic Clin Pharmacol; 6:1856-64.

· TC Akunne, BC Obi, MN Ofokansi, PC Nwonu, CO Okoli (2017). Antidiabetic activity and toxicological evaluation of the methanol-dichloromethane root bark extract of Nauclea diderrichii (De Wild) Merr. Int J Pharm Pharm Sci; 9(9):279-283.

· FN Mbaoji, AC Ezike, CS Nworu, CA Onyeto, BC Obi, TC Akunne, C Okoli, C Okpalaeke and PA Akah (2017). Sub-chronic effect of methanol-dichloromethane stem bark extract of Stemonocoleus micranthus Harms. (Fabaceae) on lipid profile and histology of liver and kidney of rats. J Pharmacogn Nat Prod, 3(2):1-6.

· FI Eze, PF Uzor, P Ikechukwu, BC Obi, PO Osadebe (2019). In vitro and in vivo models for anti-inflammation: An evaluative review. INNOSC Theranostics and Pharmacological Sciences. 2(2):3-15.

· A Ibezim, EA Onoabedje, IC Adaka, KO Omeje, US Onoabedje, BC Obi(2020). Carboxamides Bearing Sulfonamide Functionality as Potential Novel Phospholipase A2 Inhibitors. ChemistrySelect 5(45):14416-14421.

· A Ibezim, MN Ofokansi, X Ndukwe, CS Chiama, BC Obi, Ogechukwu N Isiogugu, Peter E Ikechukwu, Akachukwu M Onwuka, Stella A Ihim, Jonnie N Asegbeloyin, Ngozi J Nwodo. (2022). Evaluation of anti-malarial potency of new pyrazole-hydrazine coupled to Schiff base derivatives. Malaria Journal 21(1):1-9.

· DI Ugwuja, U Okoro, S Soman, A Ibezim, D Ugwu, R Soni, B Obi, J Ezugwu, O Ekoh. (2021). New glycine derived peptides bearing benzenesulphonamide as an antiplasmodial agent. New Journal of Chemistry 45(7):3660-3674.

· Ani C, Ojobor C, Uchenna S, Ezeanyika LUS, Obi BC (2020). Influence of Age, Sex and Body Mass Index on the Levels of Glycosylated Haemoglobin among Non-Diabetic Nigerian Population (2019). Asian Journal of Biochemistry, Genetics and Molecular Biology. 2(1):1-7.

· PE Joshua, CG Enwelu, BC Obi, R A, C Ononiwu, O Orhonigbe, E Alumanah (2022). Improvement of biochemical and hematological parameters in alloxan-induced diabetic rats via administration of ethanol extract of Garcinia kola seeds. International Journal of Diabetes in Developing Countries. 1-8.

· OD Warren, BC Obi, UC bonyi and TC Akunne (2021). Immunomodulatory activity on specific immune function in albino mice exposed to extract and fractions of Zapoteca portoricensis (Jacq) HM. Hernández Roots European Journal of Medicinal Plants 32(2): 41-50.

· O Okpe, PE Joshua, BC Obi, OFC Nwodo (2023). Vitex doniana: in vitro antioxidant, membrane stabilization potential and protective impact against Plasmodium berghei-passaged mice. Research Journal of Pharmacognosy (RJP) 10(3):15–23.

· Akpa PA, Peter IE, Onwuka AM, Obi BC, Akunne MO, Nworu CS, Ejikeme PM, Akunne TC, Attama AA Akah PA (2023). Nanotheranostics: platforms, current applications, and mechanisms of targeting in breast and prostate cancers. J. Nanotheranostics, 4, 346–383.

· West African Society for Pharmacology (WASP)-2017, Cotonou, Benin.

· West African Society for Pharmacology, Port Harcourt, Nigeria, 2019.

· Drug Discovery Africa 2017 Conference and Workshop, Ile-Ife, Nigeria. 2017

· Conference of the Organization for Women in Science for the Developing World (OWSD), Enugu State, Nigeria, 2017, 2022

· International Conference on Polymer Development and Applications, Enugu State. Nigeria. 2016.

· Sub-Regional Scientific Conference of the Western Africa Network of Natural Products Research Scientists (WANNPRES), Nigeria, 2018.

· Chemical Society Conference and Workshop – Enugu, 2019.

· National Association of Pharmacists in Academia – 18th National Scientific Conference, Nigeria 2020.

· International Conference on Biologics Research and Development – Enugu, Nigeria, 2019, 2021

· International Conference on Pharmaceutical Sciences and Industry, Enugu, Nigeria, 2020.

· Scientific and Novel Juvenilia Batten (SNJB) International Conference (Pharmacon-2020), India.

· Professor Theophine Akunne, PhD

Department of Pharmacology and Toxicology

Faculty of Pharmaceutical Sciences

University of Nigeria, Nsukka, Enugu State, Nigeria.

Email: theophine.akunne@unn.edu.ng

· Professor Chibuike C. Udenigwe, PhD

School of Nutritional Sciences

Faculty of Health Sciences

Cross-appointment, Department of Chemistry and Biomolecular Sciences

University of Ottawa, Ottawa, ON, Canada.

Email: cudenigwe@uottawa.ca

· Professor Apollinaire Tsopmo, PhD

Department of Chemistry

Faculty of Science

Carleton University, Ottawa, ON, Canada.

Email: apollinairetsopmo@cunet.carleton.ca