Behrad Saeedi
North Vancouver,BC
Summary
Diligent scientist organized in handling documentation, recordkeeping and data analysis. Dedicated to executing protocols to meet study objectives and requirements. Extensive experience with radionuclide production, purification, radiolabeling, quality control, and preclinical studies.
Overview
5
5
years of professional experience
1
1
Certification
Work History
Research Assistant
UBC/TRIUMF
Vancouver, British Columbia
09.2022 - 08.2024
- Utilized medical cyclotron to design, develop, and optimize the production of Er-165 for SPECT imaging as well as targeted Auger electron therapy of cancer and implemented a novel purification method.
- Performed quality control experiments on purified radionuclides through ICP-MS and HPGe gamma spectroscopy (chemical and radionuclidic purity).
- Performed radiolabeling experiments with Ac-225, Lu-177, Er-165, Tb-161, and Cu-64 using Crown-TATE, DOTA-TATE, and PSMA-617.
- Performed serum stability experiments using both radio-TLC and radio-HPLC.
- Prepared [165Er]Er-PSMA-617 radiotracer for injection in LNCaP tumor-bearing mice.
- Acquired and analyzed SPECT/PET/CT images.
- Executed a range of in vitro experiments involving cell uptake, internalization, and clonogenic assays with different radiotracers.
- Prepared comprehensive reports summarizing research findings.
- Managed multiple research projects simultaneously while ensuring accurate record keeping using Microsoft Excel.
- Published the results in three separate publications.
Laboratory Technician
ARTMS Inc.
Burnaby, British Columbia
10.2021 - 06.2023
- Manufactured Zn-68, Mo-99, Ni-64, and Y-89 solid targets for irradiation at medical cyclotrons to produce Ga-68, Tc-99m, Cu-64, and Zr-89 using a variety methods.
- Developed and optimized purification processes for Ga-68, Tc-99m, Cu-64, and Zr-89 production using Trasis automated synthesis unit and other units including ARTMS's dissolution box.
- Performed quality control experiments using ICP-MS, ICP-OES, and surface profilometer.
- Collected, analyzed, and reported data to the supervisor in a timely manner.
- Followed standard operating procedures to ensure accuracy and reproducibility of results.
Laboratory Technician
SGS Canada
Burnaby, British Columbia
01.2020 - 10.2021
- Recorded control values from technical instruments to maintain reliability and validity of test results.
- Prepared, processed and analyzed potash, fertilizer, and sulphur samples.
- Maintained clean and fully operational laboratory equipment.
- Performed various physical and chemical quality control tests such as ICP-MS, ICP-OES, total nitrogen analysis, screens (particle size distribution), moisture determination, quality index, degradation, and chloroform extraction (oil content), carbon, ash, and acidity determination on potash and sulfur samples.
- Followed standard operational procedures at all times to obtain valid and accurate results.
Research Assistant
Simon Fraser University
Burnaby, British Columbia
05.2019 - 09.2019
- Operated lab's supercritical fluid chamber.
- Investigated solubility of Polypropylene in supercritical Pentane
- Deposited films of atactic and isotactic Polypropylene
- Presented the results to the chemistry alumni at the end of the project
- Improved knowledge of supercritical fluid film formation in order to contribute in relevant and productive ways.
Education
Master of Science - Radiopharmacy And Chemistry
The University of British Columbia
Vancouver, BC08-2024
Bachelor of Science - Chemistry
Simon Fraser University
Burnaby, BC12-2019
Skills
- Technical Writing
- Recordkeeping
- Research Paper Writing
- Experimental Design
- Microsoft Office
- ICP-MS and ICP-OES
- HPGe Gamma Spectroscopy
- Experience with Dose Calibrators and X-ray Detection
- Radio-TLC, Radio-HPLC, and LC-MS
- Cyclotron Target Manufacturing (Melting, Electroplating, Sealing, and etc)
- SPECT/PET/CT Image Analysis
- Radiolabeling
- Preclinical Animal Studies with Radiotracers
- Nuclear Energy Worker
- Experience with Ac-225, Lu-177, Er-165, Tb-161, and Cu-64 Radiochemistry
- Radionuclide and Radiotracer Purification
- Sequence Automation Using Trasis, Fastlab, and other Units
Accomplishments
- Young Investigator Award (YIA) from Society of Nuclear medicine and Molecular Imaging (SNMMI 2024) for my work on the development of Er-165 as a promising candidate for SPECT imaging (UBC)
- Presenter award at the first annual NFRF T symposium for the best poster presentation on Er-165 (UBC)
- Walter C. Sumner Fellowship for my research performed on Er-165 as a novel radionuclide for targeted Auger electron therapy of cancer (UBC)
- The University of British Columbia 4YF Award that supports best graduate students (UBC)
- First class with distinction graduate (SFU and UBC)
- 95% CGPA (UBC)
- 4.02 CGPA (SFU)
- Multiple Honor Rolls and President Honor Rolls recipient (SFU
- Canadian Society for Chemistry (CSC) silver medal award recipient (SFU)
- Dr. Ivor Fleming USRA recipient (SFU)
- TransCanada Pipelines research scholarship in Chemistry recipient (SFU)
- BC secondary school academic excellence entrance scholarship recipient (SFU)
- Chemistry undergraduate scholarship recipient (SFU)
- Quadra Chemicals LTD. scholarship recipient (SFU)
- Multiple open scholarships and alumni scholarships recipient (SFU)
Languages
English
Native/ Bilingual
Persian
Native/ Bilingual
Certification
- Nuclear Energy Worker (NEW)
- Workplace Hazardous Materials Information System (WHMIS)
- Transportation of Dangerous Goods (TDG)
Publications
- Saeedi Saghez, B., Yang, H., & Radchenko, V. (2024). High Separation Factor, High Molar Activity, and Inexpensive Purification Method for the Production of Pure 165Er. Inorganic Chemistry. https://doi.org/10.1021/acs.inorgchem.3c03166
- Saeedi Saghez, B., Yang, H., & Radchenko, V. (n.d.). A High Separation Factor and High Molar Activity Purification for the Production of Er-165. Journal of Nuclear Medicine. https://jnm.snmjournals.org/content/65/supplement_2/241309
- Yousefi, N., Saeedi Saghez, B., Pettipas, R. D., Kelly, T. L., & Kaake, L. G. (2021). The role of solvent additive in polymer crystallinity during physical supercritical fluid deposition. New Journal of Chemistry, 45(26), 11786–11796. https://doi.org/10.1039/d1nj00362c
- Yousefi, N., Saeedi Saghez, B., Pettipas, R. D., Kelly, T. L., & Kaake, L. G. (2021a). Physical supercritical fluid deposition of polymer films: controlling the crystallinity with pressure. Materials Chemistry Frontiers. https://doi.org/10.1039/d0qm00403k
- Dunling, E., Mason, J., Saeedi Saghez, B., Lacroix, M., Childs, D., Borjian, S., & Schaffer, P. (2022). Recovery and purification of Zn-68 after cyclotron irradiation and Ga-68 recovery. Nuclear Medicine and Biology, 114-115, S43—S44. https://doi.org/10.1016/s0969-8051(22)02178-3
References
References available upon request.
Timeline
Research Assistant
UBC/TRIUMF
09.2022 - 08.2024
Laboratory Technician
ARTMS Inc.
10.2021 - 06.2023
Laboratory Technician
SGS Canada
01.2020 - 10.2021
Research Assistant
Simon Fraser University
05.2019 - 09.2019
Master of Science - Radiopharmacy And Chemistry
The University of British Columbia
Bachelor of Science - Chemistry
Simon Fraser University
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