BAL RAM ADHIKARI
Brampton
Summary
Meticulous and proficient aspiring Research and Development Scientist with 10+ years’ experience of overseeing scientific research operations (microbiology and analytical chemistry labs), point of care diagnostics, patent writing, product commercialization, project management, report writing, conducting data analysis, and collaborating with various industrial partners. Well versed in maintaining regulatory compliance, overseeing day to day laboratory QC compliances, and generating reports.
Overview
14
14
years of professional experience
Work History
Scientist
McMaster University
01.2022
- Prepared aptamer/DNA/DNAzymes for the design of point of care devices through conjugation chemistry (Protein-DNA, redox chemical-DNA, nanoparticles-DNA), purified the product through SDS-PAGE and quantified the product through yield percentage calculator
- Preparation of bacterial cultures/purifications with full aseptic techniques in BSC II cabinet
- Designed/conceptualized various aptamer/DNA/DNAzymes based assays for the detection of E
- Coli/COVID-19/Sub-variants-BA.5
- Drafted, reviewed, and filed various patents
- Participated/played crucial role for the technology transfer in close collaboration with various industrial partners (ZenTek)
- Oversaw literature reviews and manuscript writing by defining objectives, coordinating team efforts, and ensuring quality, ensuring meticulously written literature.
Scientist
Anasens Inc/University of Montreal
01.2018 - 01.2022
- Oversaw the project management by monitoring evaluation/team management and ensured project accomplishment on time
- Optimized DNA synthesis and purification methods by evaluating existing methods, experimenting with variables, and utilizing advanced tech, enhancing DNA yield
- Discussed/negotiated with various stake holders for the design and cost of microfluidic or electrochemical chips to ensure cost-effective custom designed point of care devices
- Designed and validated various DNA based handheld medical devices for cardiovascular markers (urea/creatinine/potassium) by using electrochemical readout.
Research assistant
Lakehead University
01.2013 - 01.2018
- Designed and evaluated novel bifunctional technology for the bacterial disinfection and wastewater treatment in collaboration with Thunder Bay municipality
- Designed and executed electrochemical based point of care diagnostics for various biomarkers; acetaminophen, valacyclovir, alcohol and studied their bioavailability
- Conducted lectures, grading, labs etc for physical chemistry/microbiology in undergraduate level (10-15 students)
- Managed overall lab (total 25 team members), ordered lab consumables, maintained inventory.
Microbiologist
Ministry of Health and Population, National Public Health Laboratory, Nepal
01.2008 - 01.2012
- Conducted Nationwide antimicrobial resistance surveillance of selected disease pathogens (S
- Typhi, E
- Coli, S
- Pneumoniae, P
- Aeruginosa, S
- Aureus) by collaborating with nationwide territorial lab
- Set up nationwide sample collection guidelines, developed network to send the collected samples by maintaining cold chain and performed/supervised antibiotic susceptibility test in the microbiology lab
- Conducted nationwide influenza surveillance programme by establishing focal lab throughout the nation in close collaboration with world health organization (WHO)
- Collected samples from influenza like illness (ILI) personnel, established guidelines to submit those samples to the National Public Health Laboratory by maintaining cold chain in viral transport media (VTM)
- Carried out sample test through Real-Time (RT) PCR at the molecular diagnostic facility
- Participated/led standard operating procedure (SOP) development for various experimental and instruments, trained/facilitated various training programme throughout the Country
- Communicated with various stakeholders for project successes and fund review
- Overall managed and supervised microbiology laboratory and BSL-2 molecular laboratory (Total 10 people).
Education
Post graduate diploma - Regulatory Affairs
Academy of Applied Pharmaceutical Sciences (AAPS)
Toronto, ONPhD - Biotechnology (electrochemistry and point of care devices)
Lakehead University
Thunder Bay, ONMaster's degree - Microbiology
Tribhuvan University
Bachelor's degree - Microbiology
Tribhuvan University
Skills
- Microbiology
- Analytical chemistry
- Project management
- Team management
- Quality assurance and control
- Biochemistry
- Data analysis
- Project development and project leadership
- Project partnership
- Effective communication
- Medical devices
- Technology transfer
- Commercialization
- Negotiation
- GLP
- GMP
Timeline
Scientist
McMaster University
01.2022
Scientist
Anasens Inc/University of Montreal
01.2018 - 01.2022
Research assistant
Lakehead University
01.2013 - 01.2018
Microbiologist
Ministry of Health and Population, National Public Health Laboratory, Nepal
01.2008 - 01.2012
Post graduate diploma - Regulatory Affairs
Academy of Applied Pharmaceutical Sciences (AAPS)
PhD - Biotechnology (electrochemistry and point of care devices)
Lakehead University
Master's degree - Microbiology
Tribhuvan University
Bachelor's degree - Microbiology
Tribhuvan University
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