ASMITA YEOLA
Hamilton,Canada
Summary
Experienced genomic interpreter with proven track record of achievements in supporting clinical Oncology. Over 10+ years of experience in immunology and molecular biology. I am highly motivated, autonomous and have a proven ability to collaborate and handle multiple projects simultaneously. Excellent interpersonal, leadership and presentation skills. Ability to analyze, understand, and communicate complex scientific and medical information.
Overview
11
11
years of professional experience
Work History
Variant Analyst
Velsera (PierianDx India Pvt. Ltd.)
Pune, India
05.2022 - 05.2023
- Genetic and molecular understanding of cancer biology and signaling pathways
- Analyzing DNA sequencing data using Integrative Genomics Viewer (IGV) and curate the clinical information related to patient-specific variants from different sources such as FDA approved labels, NCCN, ASCO, ACMG guidelines, clinical trials, PubMed, GenBank, RefSeq, dbSNP, ClinVar, COSMIC, HGVS, UniProt, OncoKB, etc
- Variant annotation, classification, and prioritization
- Proficiency in communicating and understanding genetic variant details
- Experience for writing clinical interpretations for variants in cancer patients (Somatic) on a day-to-day basis within TAT
- Team player with strong leadership skills demonstrated by the contribution to learning and development of teams by sharing best practices and lessons learned from customer feedback
Graduate Student
Laval University
Quebec City, Canada
08.2015 - 12.2021
- Thesis Title: The role of T cell receptor transgenic model to study CNS autoimmunity and ERAD pathway in regulating T cell function
- 2 first author publications in the leading scientific journals
- Research was mainly focused on exploring the role of inflammatory T cells in EAE, a mouse model of multiple sclerosis (MS)
- Utilized effective communication and presentation skills to relay complex scientific findings to KOLs at 10+ national & international conferences
- Hands-on experience (but not limited to): PCR, qPCR, Electrophoresis, Microscopy, ELISA, Flow-cytometry, Immunocytochemistry (ICC) and Immunohistochemistry (IHC), Isolation, culture and handling of primary cells such T cells, B cells DCs, etc
- Cloning, Animal handling (mouse models), western blotting, etc
- Other Skills: GraphPad Prism for statistical analysis, FlowJo for flow cytometry data analysis, DNA sequencing, cloning, analysis software (CLC sequence viewer, IGB, Snapgene, etc.)
Senior Research Fellow
National Centre For Cell Science (NCCS)
Pune, India
12.2014 - 08.2015
- Assessed project focused on exploring the neurogenic potential of bone marrow stromal cells (BMSC's) following inhibition of Bmp Signaling
- Isolation and characterization of mBMSC
- Studied crosstalk between signaling pathways, neural differentiation of mBMSC
- Reviewed literature, prepared written and oral presentations, and protocols regulatory submission documents aiming to design projects
- Attended professional meetings to support and represent preliminary results
Research Assistant
The Maharaja Sayajirao University Of Baroda
Vadodara, India
09.2013 - 09.2014
- Studied the molecular basis of development and progression of vitiligo
- Project received Indo-Canadian Research Internship award and the part of this project was carried out at Université Laval, Quebec City, Canada (Apr 2014-June 2014)
Junior Research Fellow
Tata Memorial Centre
Mumbai, India
08.2012 - 09.2013
- Explored genetic predisposition to cancer from low penetrance genes & their interaction with various endogenous or environmental factors in common cancers
- Conducted a breast cancer-case control study evaluating different SNPs in xenobiotic metabolizing genes and various reproductive, lifestyle, dietary, chrono-biology & exposure variables in sporadic and familial cancers
- Studied DNA repair kinetics by gamma H2AX assay in EBV infected Lymphoblastoid cell lines of the individuals with BRCA1 deleterious mutations
Education
Ph.D. - Molecular Medicine
Université Laval
Quebec City12.2021
Master of Science - Biotechnology
Sardar Patel University
Anand, Gujarat, India06.2010
Bachelor of Science - Biotechnology
University of Pune
Loni, Maharashtra, India06.2008
Skills
- Multi-panel Flowcytometry
- FlowJo
- DNA isolation
- RNA isolation
- Protein isolation
- QPCR
- Molecular Biology techniques
- Transformations
- Transfections
- Gel electrophoresis
- WB analysis
- PCR
- PCR-Mutagenesis
- Mammalian cell culture
- Mouse model handling
Accomplishments
- Shastri Indo-Canadian Institute, Québec tuition fee exemption for Indian students, 01/01/16
- Shastri Indo-Canadian Institute, Shastri Research Grant 2013-2014, Lab- Dr. Girish Shah, Laval University and University Hospital of Québec (CHUL)
- Senior research Fellow Dec.2014, Department of Biotechnology India, National Centre for cell science NCCS, Pune, India., 12/01/14
- Junior research Fellow Aug 2012, Indian Council of Medical Research, Tata Memorial Centre, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Kharghar, Navi Mumbai, India., 08/01/12
Timeline
Variant Analyst
Velsera (PierianDx India Pvt. Ltd.)
05.2022 - 05.2023
Graduate Student
Laval University
08.2015 - 12.2021
Senior Research Fellow
National Centre For Cell Science (NCCS)
12.2014 - 08.2015
Research Assistant
The Maharaja Sayajirao University Of Baroda
09.2013 - 09.2014
Junior Research Fellow
Tata Memorial Centre
08.2012 - 09.2013
Ph.D. - Molecular Medicine
Université Laval
Master of Science - Biotechnology
Sardar Patel University
Bachelor of Science - Biotechnology
University of Pune
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