Amira Othman

I hold two Ph.D. degrees and am currently a third year resident in Molecular and diagnostic Pathology department at Queens’s university, driven by a strong commitment to continuous learning. My academic and clinical journey has taken me across four continents, allowing me to gain diverse scientific insights and pursue excellence in medicine. Committed lecturer with several years in mentoring and educating upper-level undergraduate students. Worked with full-time faculty to supplement programs to prepare students for success in career or graduate school. Created fascinating lectures and activities to explain and demonstrate difficult concepts.

• 05/2021, Edinburg, U.K., Neutrophil 2021, TLR9 Activation Impairs Neutrophil Phagocytosis and Resolution of Inflammation.
• 11/2020, Kharkiv, Ukraine, 3rd Scientific and practical internet-conference mechanisms of pathological processes development and diseases, their pharmacological correction., Aspirin-triggered pro-resolving lipids counter TLR9 signaling to promote resolution of bacterial inflammation.
• 04/2019, Montreal, QC, 33rd Scientific day of the Department of Pathology and Cell Biology, Interferonβ facilitates the resolution of pulmonary inflammation induced by E-Coli.
• 04/2014, USA
• 03/2012, Georgia, USA
• 05/2012, Florida, USA, The Association for Research in Vision and Ophthalmology (ARVO), 12/15-Lipoxygenase-Derived Eicosanoids Induce Vascular Inflammation and Angiogenic: Effects in Human Retinal Endothelial Cells: Role of NADPH oxidase and E.R. Stress.

• Enemies at the gate: how cell-free hemoglobin and bacterial infection can cooperate to drive acute lung injury during sepsis., Othman A, Filep JG., Am J Physiol Heart Circ Physiol., 07/01/21, 321, 1, H131-H134
• Β2 Integrin Regulation of Neutrophil Functional Plasticity and Fate in the Resolution of Inflammation., Sekheri M, Othman A, Filep JG., Front Immunol., 03/30/21, 12, 660760
• Roles of Neutrophil Granule Proteins in Orchestrating Inflammation and Immunity., Othman A., Sekheri M, Filep JG., FEBS J., 03/08/21
• Ifnβ Is A macrophage-derived Effector Cytokine Facilitating the Resolution of Bacterial Inflammation., Satyanarayanan, S., El Kebir, D., Soboh, S., Butenko, S., Sekheri, M., Saadi, J., Peled, N., Assi, S., Othman, A., Schif-Zuck, S., Feuermann, Y., Barkan, D., Sher, N., Filep, J. G., & Ariel, A., Nature communications, 2019, 10, 1, 3471
• Targeting Neovascularization in Ischemic Retinopathy: Recent Advances., Mohamed Al-Shabrawey, Mohamed Elsherbiny, Julian Nussbaum, Othman, A., Sylvia Megyerdi, Amany Tawfik., Expert Rev Ophthalmol., 06/2013, 8, 3, 267–286
• 12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase., Othman A., S Ahmad, S Megyerdi, R Mussell, K Choksi, KR Maddipati, (et al.)., PloS one, 2013, 8, 2
• Caspase-14: A Novel Caspase in The Retina with A Potential Role in Diabetic Retinopathy., Mohamed Al-Shabrawey, Saif Ahmad, Sylvia Megyerdi, Othman, A. Babak Baban, Tammy L. Palenski, Eui Seok Shin, Zafer Gurel, Stephen Hsu, Nader Sheibani., Mol Vis., 2012, 18, 1895–1906
• High-Mobility Group Box-1 Protein Activates Inflammatory Signaling Pathway Components and Disrupts Retinal Vascular-Barrier in The Diabetic Retina., G Mohammad, MM Siddiquei, Othman, A. M Al-Shabrawey, AMA El-Asrar., Experimental eye research, 2012, 107, 101-109

• Role of Neutrophils in Sepsis, University of Montreal, Montreal, Canada, 09/2018, 04/2022, Ph.D. candidate.
• Signaling via HLA class I and class II molecules in adult stem cells: cardiac stem cells as a model, Mansoura Research Centre for Cord Stem Cell (MARC-CSC), Mansoura, Egypt, 08/2013, 09/2016, postdoc candidate
• Mechanism of neovascularization in diabetic retinopathy, Georgia Regents University, Georgia, USA, 09/2011, 08/2012, visiting scientist
• Role of cancer stem cells in hepatocellular carcinoma, Mansoura University, Mansoura, Egypt, 10/2009, 12/2013, Ph.D Candidate.

• 10/2018, Montreal, Canada, Animal breeding and genetics, Animal Facility, Hospital Maisonneuve-Rosemont
• 2006/2015, Mansoura, Egypt, Faculty and Leadership Development Project (FLDP), certified by the University Development Centre (UDC), Mansoura, Cairo, Egypt