Skilled and accomplished cell biologist with 10+ years of experience in academic and industry settings. Strong background in mammalian cell culture and cell-based assay development. Enthusiastic researcher comfortable with working in cross-functional teams, learning cutting-edge technologies and developing novel applications. Eager to join new organization working in a fast-paced, stimulating R&D environment.
Overview
13
13
years of professional experience
Work History
Staff Scientist, T Cell Immunology
The University Of Oklahoma
02.2020 - Current
Design, conduct and validate single-cell immunoassays to characterize CAR-T cell populations on microfluidic devices (cytokine release, cytotoxicity, T cell activation and proliferation, metabolic and transcriptomic profiling).
Train research associates and members of project teams on instruments and lab methodologies and manage day-to-day experiment execution.
Actively interact with Operations, Software and Reagent teams to ensure effective technology transfer.
Support Marketing team by generating data for customer-facing marketing collateral.
Write content for user manuals/protocols, providing clear and comprehensive instructions for proper execution of processes on company’s systems.
Provide design suggestions and bug reports to software team during testing of development builds of company’s proprietary software, resulting in release of production version of system for the analysis of assay data.
Participate on project teams as biology technical lead to facilitate the team’s activities and achievement of goals.
Senior Scientist, T Cell Immunology
Berkeley Lights Inc.
02.2018 - 01.2020
Use of immunological techniques such as isolation of primary immune cell subsets, primary cell culture and expansion, transfection and viral transduction of immune cells, multicolor flow cytometry and cell-based functional assays.
Contribute to the technical development of a synthetic system for selection and expansion of antigen-specific T cells.
Serve as primary technical expert to establish novel automated, single-cell immunoassays for functional profiling of immune cells on microfluidic devices.
Support technical development of a workflow for the identification of therapeutically relevant T cell receptors (TCRs).
Fulfill project management responsibilities such as coordination of functional teams, budget estimation, resource allocation and scheduling for the release of new T cell applications on company’s platforms.
Provide accurate reporting on timelines, deliverables and project status to the executive team.
Biologist, Genome Editing
Berkeley Lights Inc.
05.2016 - 01.2018
Generate gene-edited primary human T cell lines using CRISPR-CAS9 technology.
Develop assays for automated single-cell analysis of gene-edited T cells on microfluidic devices.
Develop molecular biology pipelines for high-throughput validation of CRISPR-edited cell lines using single-cell sequencing.
Manage collaborations with academic institutions, present research findings to senior staff and contribute to preparation of research reports, manuscripts and patent filings.
Postdoctoral Research Fellow
University Of California, Berkeley
11.2010 - 03.2016
Identify new targets of cancer therapeutics by high-throughput, automated siRNA screens.
Establish a new line of research in the lab using human and mouse embryonic stem cells as model system.
Dissect the function of deubiquitinating enzymes in human cancer cells and in human embryonic stem cell differentiation.
As lab viral facility coordinator, collaborate with coordinators from different labs to establish the SOPs of the facility and to purchase and maintain equipment; train members of the lab on proper handling of lentivirus.
As lab safety coordinator, accumulate extensive knowledge in hazardous materials handling; train new lab members; maintain detailed records of the chemical inventory and of the safety procedures of the lab.
As lab microscopy facility coordinator, purchase and maintain epifluorescence and confocal microscopes; test demo version of microscopes and imaging softwares; train members of the lab on different microscopy and image analysis techniques.
Education
Ph.D. - Molecular And Cellular Biology
ZMBH, Ruprecht-Karls University
Heidelberg, DE
06.2010
Master of Science - Molecular And Cellular Biology
University of Palermo
Palermo, Italy
12.2004
Skills
Highly skilled in mammalian cell culture, focused on human primary immune cells and stem cells
Strong background in design, development and validation of cell-based assays to monitor immune responses
Expertise with automated microfluidic platforms for digital cell biology
Proven track record of successful project execution and product development
Detail-oriented and analytical, with strong work ethic, excellent problem-solving skills and ease of learning new technologies
Proven managerial attitude and experience with working in fast-paced, multi-disciplinary environments
Excellent written and oral communication skills as demonstrated by peer reviewed publications, patents and presentations
Timeline
Staff Scientist, T Cell Immunology
The University Of Oklahoma
02.2020 - Current
Senior Scientist, T Cell Immunology
Berkeley Lights Inc.
02.2018 - 01.2020
Biologist, Genome Editing
Berkeley Lights Inc.
05.2016 - 01.2018
Postdoctoral Research Fellow
University Of California, Berkeley
11.2010 - 03.2016
Ph.D. - Molecular And Cellular Biology
ZMBH, Ruprecht-Karls University
Master of Science - Molecular And Cellular Biology
Senior Scientist – Safety Rep, Capital Equipment Champion at GlaxoSmithKlineSenior Scientist – Safety Rep, Capital Equipment Champion at GlaxoSmithKline